Clinical and Immunological Features of Herpesviral Diseases in Case of HIV-Infection
Abstract
The paper discusses a range of clinical manifestation
of herpesviral affections in 353 HIV-patients. As the HIV infection
progressed, the authors have recorded changes in the immune system
that caused associated diseases or activation of opportunistic
infections. The lowering of CD4+-lymphocytes down to 200 in 1
mkl of blood resulted in the severe course of herpesviral infections.
In 25 % of cases the pathological process was generalized. More
than a half of patients had simple herpes associated with other opportunistic
infections (tuberculosis, toxoplasmosis, candidiasis)
that leaded to an increase of the lethality rate.
of herpesviral affections in 353 HIV-patients. As the HIV infection
progressed, the authors have recorded changes in the immune system
that caused associated diseases or activation of opportunistic
infections. The lowering of CD4+-lymphocytes down to 200 in 1
mkl of blood resulted in the severe course of herpesviral infections.
In 25 % of cases the pathological process was generalized. More
than a half of patients had simple herpes associated with other opportunistic
infections (tuberculosis, toxoplasmosis, candidiasis)
that leaded to an increase of the lethality rate.
About the Authors
Л. Скляр
Владивостокский государственный медицинский университет
Russian Federation
Russian Federation
Е. Маркелова
Владивостокский государственный медицинский университет
Russian Federation
Russian Federation
Н. Боровская
Владивостокский государственный медицинский университет
Russian Federation
Russian Federation
Л. Зима
Краевой клинический центр по профилактике и борьбе со СПИД
Russian Federation
Russian Federation
Е. Гапоненко
Краевой диагностический центр "Вивея"
Russian Federation
Russian Federation
L. F. Sklyar
Vladivostok State Medical University
Russian Federation
Russian Federation
E. V. Markelova
Vladivostok State Medical University
Russian Federation
Russian Federation
N. A. Borovskaya
Vladivostok State Medical University
Russian Federation
Russian Federation
L. G. Zima
Regional Clinical Centre of AIDS
Prevention and Treatment
Russian Federation
Russian Federation
E. K. Gaponenko
Regional Diagnostic Centre "Vivea"
Russian Federation
Russian Federation
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Review
For citations:
, , , , , Sklyar L.F., Markelova E.V., Borovskaya N.A., Zima L.G., Gaponenko E.K. Clinical and Immunological Features of Herpesviral Diseases in Case of HIV-Infection. Pacific Medical Journal. 2010;(3):62-64. (In Russ.)
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