Characterizing effect of thermolabile lethal toxin Yersinia Pseudotuberculosis on embryogenesis and biosynthesis of DNA, RNA and protein in embryos of sea urchin Strongylocentrotus Intermedius
Abstract
The paper discusses effect of thermolabile lethal toxin Yersinia pseudotuberculosis on embryogenesis of sea urchins
Strongylocentrotus intermedius and biosynthesis of nucleic acids
and proteins in embryo cells. As shown, the toxin has effect on
metabolic processes in cells by inhibiting synthesis of DNA and
RNA, and almost does not affect protein synthesis. The toxin is of
damaging action on sea urchin embryos in development and causes
morphological changes, thus leading to embryonic death.
Strongylocentrotus intermedius and biosynthesis of nucleic acids
and proteins in embryo cells. As shown, the toxin has effect on
metabolic processes in cells by inhibiting synthesis of DNA and
RNA, and almost does not affect protein synthesis. The toxin is of
damaging action on sea urchin embryos in development and causes
morphological changes, thus leading to embryonic death.
Keywords
Yersinia pseudotuberculosis,
thermolabile lethal toxin,
sea urchin embryos,
biosynthesis of nucleic acids and proteins
612.017.4:616-002.71:593.95
About the Authors
Н. ТерентьеваRussian Federation
Н. Тимченко
НИИ эпидемиологии и микробиологии СО РАМН
Russian Federation
Russian Federation
Е. Персиянова
НИИ эпидемиологии и микробиологии СО РАМН
Russian Federation
Russian Federation
В. Рассказов
Russian Federation
N. A. Terentieva
Pacific Institute of Bioorganic Chemistry
Russian Federation
Russian Federation
N. F. Timchenko
Research
Institute of Epidemiology and Microbiology, SB RAMS
Russian Federation
Russian Federation
E. V. Persiyanova
Research
Institute of Epidemiology and Microbiology, SB RAMS
Russian Federation
Russian Federation
V. A. Rasskazov
Pacific Institute of Bioorganic Chemistry
Russian Federation
Russian Federation
References
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Review
For citations:
, , , , Terentieva N.A., Timchenko N.F., Persiyanova E.V., Rasskazov V.A. Characterizing effect of thermolabile lethal toxin Yersinia Pseudotuberculosis on embryogenesis and biosynthesis of DNA, RNA and protein in embryos of sea urchin Strongylocentrotus Intermedius. Pacific Medical Journal. 2010;(3):81-84. (In Russ.)
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