REGULATION OF NEUTRAL STEM CELL GROWTH AND DIFFERENTIATION USING MICROSTRUCTURED NANO-HETEROGENOUS MATRIX MATERIALS
Abstract
The authors present results of studies devoted to the
development of microstructured nano-heterogenous matrix materials
that ensure regulation of cell growth and differentiation
to create artificial tissue implants based upon cell bio-polymer
constructions. To create microstructured matrixes, the authors
have used original bio-polymer compounds of protein and carbohydrate
origin modified and positioned in the compound via
multiport injection spraying unit. Using neutral stem cell cultures
allows demonstrating the capability of one matrix types to
induce directed cell growth and differentiation along the composition
tracks, and of other matrix types - to inhibit differentiation
with cell congregation positioning.
development of microstructured nano-heterogenous matrix materials
that ensure regulation of cell growth and differentiation
to create artificial tissue implants based upon cell bio-polymer
constructions. To create microstructured matrixes, the authors
have used original bio-polymer compounds of protein and carbohydrate
origin modified and positioned in the compound via
multiport injection spraying unit. Using neutral stem cell cultures
allows demonstrating the capability of one matrix types to
induce directed cell growth and differentiation along the composition
tracks, and of other matrix types - to inhibit differentiation
with cell congregation positioning.
About the Authors
В. Кумейко
Институт биологии моря им. А.В. Жирмунского ДВО РАН; Дальневосточный государственный университет
Russian Federation
Russian Federation
Ю. Хотимченко
Институт биологии моря им. А.В. Жирмунского ДВО РАН
Russian Federation
Russian Federation
А. Астахова
Институт биологии моря им. А.В. Жирмунского ДВО РАН
Russian Federation
Russian Federation
А. Щеблыкина
Институт биологии моря им. А.В. Жирмунского ДВО РАН
Russian Federation
Russian Federation
Н. Зюмченко
Дальневосточный государственный университет
Russian Federation
Russian Federation
Н. Токмакова
Дальневосточный государственный университет
Russian Federation
Russian Federation
А. Анисимова
Дальневосточный государственный университет
Russian Federation
Russian Federation
С. Титов
Дальневосточный государственный университет
Russian Federation
Russian Federation
Е. Демиденко
Институт биологии моря им. А.В. Жирмунского ДВО РАН
Russian Federation
Russian Federation
А. Борейко
Институт биологии моря им. А.В. Жирмунского ДВО РАН
Russian Federation
Russian Federation
И. Дюйзен
Институт биологии моря им. А.В. Жирмунского ДВО РАН
Russian Federation
Russian Federation
И. Кирсанова
Дальневосточный государственный университет
Russian Federation
Russian Federation
А. Анисимов
Дальневосточный государственный университет
Russian Federation
Russian Federation
V. V. Kumeiko
Institute of Marine Biology named after A.V. Zhirmundsky, FEB RAS; Far Eastern National University
Russian Federation
Russian Federation
Yu. S. Khotimchenko
Institute of Marine Biology named after A.V. Zhirmundsky, FEB
RAS
Russian Federation
Russian Federation
A. A. Astakhova
Institute of Marine Biology named after A.V. Zhirmundsky, FEB
RAS
Russian Federation
Russian Federation
A. V. Scheblyikina
Institute of Marine Biology named after A.V. Zhirmundsky, FEB
RAS
Russian Federation
Russian Federation
N. E. Zyumchenko
Far Eastern National University
Russian Federation
Russian Federation
N. P. Tokmakova
Far Eastern National University
Russian Federation
Russian Federation
A. A. Anisimova
Far Eastern National University
Russian Federation
Russian Federation
S. I. Titov
Far Eastern National University
Russian Federation
Russian Federation
E. V. Demidenko
Institute of Marine Biology named after A.V. Zhirmundsky, FEB
RAS
Russian Federation
Russian Federation
A. A. Boreiko
Institute of Marine Biology named after A.V. Zhirmundsky, FEB
RAS
Russian Federation
Russian Federation
I. V. Dyuizen
Institute of Marine Biology named after A.V. Zhirmundsky, FEB
RAS
Russian Federation
Russian Federation
I. A. Kirsanova
Far Eastern National University
Russian Federation
Russian Federation
A. P. Anisimov
Far Eastern National University
Russian Federation
Russian Federation
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Review
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, , , , , , , , , , , , , Kumeiko V.V., Khotimchenko Yu.S., Astakhova A.A., Scheblyikina A.V., Zyumchenko N.E., Tokmakova N.P., Anisimova A.A., Titov S.I., Demidenko E.V., Boreiko A.A., Dyuizen I.V., Kirsanova I.A., Anisimov A.P. REGULATION OF NEUTRAL STEM CELL GROWTH AND DIFFERENTIATION USING MICROSTRUCTURED NANO-HETEROGENOUS MATRIX MATERIALS. Pacific Medical Journal. 2010;(2):26-31. (In Russ.)
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