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ОЦЕНКА ВОЗМОЖНОСТИ ПРИМЕНЕНИЯ КАРРАГИНАНА ДЛЯ АДРЕСНОЙ ДОСТАВКИ ПРОТИВООПУХОЛЕВЫХ ЛЕКАРСТВЕННЫХ СРЕДСТВ

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Аннотация

The authors estimate binding ability of ι-carrageenan
with respect to anti-tumor drugs - cyclophosphamide and
dacarbazine. The carrageenan selectively bind and retain molecules
of dacarbazine in the polysaccharidic gel medium structure
due to chemical adsorption processes that can be used to create
new all-inclusive drugs for recipient-oriented delivery of drug
substances with controlled release of an active compound.

Об авторах

М. Ю. Хотимченко
Владивостокский государственный медицинский университет
Россия


О. А. Шокур
Дальневосточный государственный медицинский университет
Россия


Н. Е. Ламаш
Институт биологии моря имени А.В. Жирмунского ДВО РАН
Россия


M. Khotimchenko
Vladivostok State Medical University
Россия


O. Shokur
Far-Eastern State Medical University
Россия


N. Lamash
Institute of Marine Biology named after A.V. Zhirmundsky, FEB RAS
Россия


Список литературы

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Для цитирования:


Хотимченко М.Ю., Шокур О.А., Ламаш Н.Е., ., ., . ОЦЕНКА ВОЗМОЖНОСТИ ПРИМЕНЕНИЯ КАРРАГИНАНА ДЛЯ АДРЕСНОЙ ДОСТАВКИ ПРОТИВООПУХОЛЕВЫХ ЛЕКАРСТВЕННЫХ СРЕДСТВ. Тихоокеанский медицинский журнал. 2010;(2):59-62.

For citation:


., ., ., Khotimchenko M.Yu., Shokur O.A., Lamash N.E. Estimating probable aplication ofcaragenans for recipient-oriented delivery of anticancer drugs. Pacific Medical Journal. 2010;(2):59-62. (In Russ.)

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ISSN 1609-1175 (Print)