Effect of Chitosans of Diferent Molecular Mas on Ehrlich Adenocarcinoma Growth and Efficiency of Cyclophosphane in Mice
Abstract
Using models of passaged Ehrlich adenocarcinoma
in mice, the authors have studied effects of chitosans with different
molecular mass (190 to 300 and 50 to 190 kDa). The chitosans
were introduced orally at a dose of 50 and 100 mg/kg. Both
specimens did not have effect on the Ehrlich adenocarcinoma
growth but had reliable anti-tumor effect of cyclophosphane.
in mice, the authors have studied effects of chitosans with different
molecular mass (190 to 300 and 50 to 190 kDa). The chitosans
were introduced orally at a dose of 50 and 100 mg/kg. Both
specimens did not have effect on the Ehrlich adenocarcinoma
growth but had reliable anti-tumor effect of cyclophosphane.
About the Authors
Е. Зуева
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
Т. Разина
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
Е. Амосова
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
С. Крылова
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
К. Лопатина
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
Л. Ефимова
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
Е. Сафонова
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
О. Рыбалкина
НИИ фармакологии СО РАМН
Russian Federation
Russian Federation
Ю. Хотимченко
Институт биологии моря им. А.В. Жирмунского ДВО РАН
Russian Federation
Russian Federation
E. P. Zueva
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
T. G. Razina
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
E. N. Amosova
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
S. G. Kryilova
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
K. A. Lopatina
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
L. A. Efimova
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
E. A. Safonova
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
O. Yu. Ryibalkina
Research Institute of Pharmacology, SB RAMS
Russian Federation
Russian Federation
Yu. S. Khotimchenko
Institute of Marine Biology named after
A.V. Zhirmundsky, FEB RAS
Russian Federation
Russian Federation
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Review
For citations:
, , , , , , , , , Zueva E.P., Razina T.G., Amosova E.N., Kryilova S.G., Lopatina K.A., Efimova L.A., Safonova E.A., Ryibalkina O.Yu., Khotimchenko Yu.S. Effect of Chitosans of Diferent Molecular Mas on Ehrlich Adenocarcinoma Growth and Efficiency of Cyclophosphane in Mice. Pacific Medical Journal. 2010;(2):82-84. (In Russ.)
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