Effect of echinochrome on kidney structure and metabolism in 40-day white rats exposed prenatally to lead nitrate
Abstract
The authors have studied effect produced by echinochrome A on the kidneys morphology and functional parameters using model of 40-day white rats exposed prenatally to lead nitrate. The studies were aimed at defining parameters of free-radical oxidation in kidney homogenates and blood serum. The lead nitrate induced oxidative stress and destructive changes in kidneys. Echinochrome A prevented these disturbances.
About the Authors
E. Yu. Prieszheva
Khabarovsk Branch of the Far Eastern Research Centre of Physiology and Respiration Pathology, RAMS, Siberian Branch - Research Centre of Motherhood and Childhood Protection
Russian Federation
Russian Federation
O. A. Lebedko
Khabarovsk Branch of the Far Eastern Research Centre of Physiology and Respiration Pathology, RAMS, Siberian Branch - Research Centre of Motherhood and Childhood Protection
Russian Federation
Russian Federation
B. Ya. Ryizhavskiy
Far Eastern State Medical University
Russian Federation
Russian Federation
V. K. Kozlov
Khabarovsk Branch of the Far Eastern Research Centre of Physiology and Respiration Pathology, RAMS, Siberian Branch - Research Centre of Motherhood and Childhood Protection
Russian Federation
Russian Federation
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Review
For citations:
Prieszheva E.Yu., Lebedko O.A., Ryizhavskiy B.Ya., Kozlov V.K. Effect of echinochrome on kidney structure and metabolism in 40-day white rats exposed prenatally to lead nitrate. Pacific Medical Journal. 2009;(3):58-60. (In Russ.)
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