Role of hypoxemia in forming immune disorders and haemostasis in patients with chronic obstructive pulmonary disease
Abstract
The authors have examined two groups of patients with chronic obstructive pulmonary disease (24 patients without hypoxemia and 17 patients with hypoxemia) and revealed interdependence between hypoxemia level and system inflammation and haemosta-sis. The levels of systemic inflammation markers, hypercoagulation and fibrinolytic system suppression in patients with hypoxemia was considerably higher than those of the patients with normal parameters of the arterial blood oxygen saturation that was indicative of a considerable role of hypoxemia in pathogenesis of inflammatory reaction in case of chronic obstructive pulmonary disease.
Keywords
УДК616.24-033.3-036.12-06:612.017.1
About the Authors
M. F. Kinyaikin
Vladivostok State Medical University
Russian Federation
Russian Federation
G. I. Sukhanova
Vladivostok State Medical University
Russian Federation
Russian Federation
I. V. Naumova
Vladivostok State Medical University
Russian Federation
Russian Federation
Т. А. Kuznetsova
Research Centre of Epidemiology and Microbiology of the RAMS, Siberian Branch
Russian Federation
Russian Federation
A. Ya. Ovchinnikov
Vladivostok State Medical University
Russian Federation
Russian Federation
I. M. Poletaeva
Vladivostok State Medical University
Russian Federation
Russian Federation
V. M. Beznis
Vladivostok State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Kinyaikin M.F., Sukhanova G.I., Naumova I.V., Kuznetsova Т.А., Ovchinnikov A.Ya., Poletaeva I.M., Beznis V.M. Role of hypoxemia in forming immune disorders and haemostasis in patients with chronic obstructive pulmonary disease. Pacific Medical Journal. 2009;(3):120-122. (In Russ.)
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