Prolonged epidural infusion in preoperative treatment of patients with a critical ischemia of the legs in case of the chronic pain
Abstract
The analysis of treatment of a pain syndrome in a complex of preoperative treatment at 60 patients with a critical ischemia of the legs is done. We used the epidural anesthesia of the Ropivacain (control), epidural anesthesia and intramuscular Ketoprophen (1st group), and also epidural anesthesia, Ketoprophen and analgetic doze of the Kethamine (2nd group). It is shown, that multimodal and preventive method of preoperative treatment statistically significantly improves the peripheral blood flow, and also allows influencing the pathogenesis of the chronic ischemic pain syndrome due to effective efferent blockade, anti-prostaglandine action of the Ketoprophen and blockade of NM DA-receptors.
About the Authors
A. Yu. NovikovRussian Federation
I. E. Golub
Russian Federation
K. V. Maistrovskiy
Russian Federation
References
1. Боль и аналгезия / Машфорд М.Л., Купер М.Г., Кохен М.Л. и др. — М.: Литера, 2004.
2. Казаков Ю.И., Белов И.В., Хатыпов М.Г., Ситкин С.И. // Ангиология и сосудистая хирургия. — 2004. - Т. 10, № 4. - С. 73-77.
3. Карпов И.А., Овечкин А.М., Теплых Б.А. // Регионарная анестезия и лечение боли. — М. — Тверь, 2004. - С. 60-63.
4. Кукушкин М.Л. //Боль. - 2003. -№1.- С. 5-12.
5. Лебедева Р.Н., Никода В.В. // Фармакотерапия острой боли. — М. :Аир-Арт, 1998. — С. 47—55.
6. Овечкин А.М., Свиридов С.В. // Регионарная анестезия и лечение острой боли. — 2006. — Т. 1, № 0. — С. 68-69.
7. Осипова Н.А., Никода В.В. //Анестезиология и реаниматология. — 2003. — № 5. — С. 4—9.
8. Breivik H. // Pain / An Updated Review. - Seattle, 2002. - P. 337-349.
9. Kehlet H. // Br. J. Anesth. - 1997. - Vоl. 78. - P. 606- 617, 195.
10. Kohrs R., Direux M. // Anest. Analg. - 1998. - Vol. 87. - P. 1186-1193.
11. Rosenfeld B.A., Beattie C., Christopherson R. et al. // Anesthesiology. - 1993. - Vol. 79. - P. 435-443.
12. Pfenninger E., Himmelseher S. // Anaesthesist. — 1997. — Bd 46, Suppl. 1. - S. 47-54.
13. Stubhaug A., Breivic H., Eide P.K. et al. // Proceedings of the 8th World Congress on Pain. - Seattle, 1996. - P. 173-187.
14. Willetts J., Balster R.L. // J. Pharmacol. Exp. Ther. - 1989. - Vol. 251. - P. 627-633.
Review
For citations:
Novikov A.Yu., Golub I.E., Maistrovskiy K.V. Prolonged epidural infusion in preoperative treatment of patients with a critical ischemia of the legs in case of the chronic pain. Pacific Medical Journal. 2008;(1):46-48. (In Russ.)