MODERN IDEAS ABOUT THE MECHANISM OF ANTINEOPLASTIC ACTION OF METHOTREXATE AND RESISTANCE TO IT
Abstract
The review of the literature devoted to mechanisms of action of methotrexate and prospects of chemotherapy of tumors. Prospects of development of chemotherapy and biotherapy seem to be optimistic in the situations when the potential of the surgical method of treatment of tumors seems practically exhausted. Constant intensive research in clinical and experimental oncology raises hopes for the further progress in this area and increase in an arsenal of struggle with malignant tumors.
About the Authors
D. V. Nevozhaj
Institute of immunology and experimental therapy of the Polish academy of sciences
Poland
Wrozlaw
Poland
Wrozlaw
R. Budzynskaya
Institute of immunology and experimental therapy of the Polish academy of sciences
Poland
Wrozlaw
Poland
Wrozlaw
U. Kan’skaya
Institute of immunology and experimental therapy of the Polish academy of sciences
Poland
Wrozlaw
Poland
Wrozlaw
M. Yagello
Institute of immunology and experimental therapy of the Polish academy of sciences
Poland
Wrozlaw
Poland
Wrozlaw
Yu. Boratyn’sky
Institute of immunology and experimental therapy of the Polish academy of sciences
Poland
Wrozlaw
Poland
Wrozlaw
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Review
For citations:
Nevozhaj D.V., Budzynskaya R., Kan’skaya U., Yagello M., Boratyn’sky Yu. MODERN IDEAS ABOUT THE MECHANISM OF ANTINEOPLASTIC ACTION OF METHOTREXATE AND RESISTANCE TO IT. Pacific Medical Journal. 2006;(4):12-16. (In Russ.)
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