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CELLULAR AND NEUROCHEMICAL MECHANISMS OF THE CORTEX EPILEPTOGENESIS

Abstract

The review of the literature devoted to morphology and pathogenesis of epilepsy. Despite of the big variety of ethio-pathogenetic factors of this disease and the various neural networks, pathogenetic processes have some similar moments which concern laws of formation of the centers of damage and neuron devastation. These components in hippocampus formation include nitroxide-ergic cage neurons and glutamate-ergic pyramid cells, parvalbumin- and calbindin-containing interneurons of the hippocampus and calretinin neurons of the gate of fascia serrata. In neo-cortex these are parvalbumin cage cells and cells – candelabrums, calbindin gliacytes and cells of CajalRetzius, and also astrocytes and vessels in their nearest microenvironment.

About the Author

Yu. V. Dudina
Vladivostok State Medical University
Russian Federation


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Review

For citations:


Dudina Yu.V. CELLULAR AND NEUROCHEMICAL MECHANISMS OF THE CORTEX EPILEPTOGENESIS. Pacific Medical Journal. 2005;(4):11-17. (In Russ.)

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ISSN 1609-1175 (Print)