ACTION OF BIOLOGICALLY ACTIVE ADDITIVE TINROSTIM ON CYTOKINE LEVEL AT ONCO-GYNECOLOGIC PATIENTS
Abstract
Total 80 women suffering by onco-gynecologic diseases are examined. Part of the patients in a complex of pre- and postoperative therapy have been added the biologically active additive ”Tinrostim“. In dynamics of the postoperative period the patients with not purulent complications still had the ability to cytokine production; at severe purulent complications this ability was reduced. The use of ”Tinrostim“ at a stage of preoperative care resulted in moderate increase in the level of the tumors necrosis factor -α, IL-4 and γ- interferon in blood in the postoperative period. The use of ”Tinrostim“ in a complex of postoperative treatment was accompanied by increase of cytokine production only in case of not severe complications.
About the Authors
T. S. Zaporozhets
Scientific Research Center of Epidemiology and Microbiology Siberian Branch of the Russian Academy of Medical Science;
Primorsky Regional Oncological Clinic
Russian Federation
Vladivostok
Russian Federation
Vladivostok
T. L. Gritsyuk
Scientific Research Center of Epidemiology and Microbiology Siberian Branch of the Russian Academy of Medical Science;
Primorsky Regional Oncological Clinic
Russian Federation
Vladivostok
Russian Federation
Vladivostok
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Review
For citations:
Zaporozhets T.S., Gritsyuk T.L. ACTION OF BIOLOGICALLY ACTIVE ADDITIVE TINROSTIM ON CYTOKINE LEVEL AT ONCO-GYNECOLOGIC PATIENTS. Pacific Medical Journal. 2005;(4):29-32. (In Russ.)
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