Photodynamic therapy in the treatment of locally advanced esophageal cancer
https://doi.org/10.17238/PmJ1609-1175.2017.3.75-77
Abstract
Analyzed the results of endoscopic photodynamic therapy (EPT) in 17 patients of 47-76 years with inoperable locally advanced squamous esophagus cancer and with dysphagia of II-III stages. Complete restoration of the esophagus lumen was noted in 2 patients, incomplete (partial) - in 14 patients. The procedure was ineffective in one case. In patients with incomplete effect or with tumor recurrence, stenting of the esophagus was subsequently carried out. Thus, EPT allowed to achieve clinical remission of the disease and improvement in the quality and life span of 16 of the 17 inoperable patients with locally advanced esophageal cancer.
About the Authors
A. N. Tumanina
Primorskiy Regional Oncologic Center
Russian Federation
Russian Federation
A. A. Polezhaev
Pacific State Medical University
Russian Federation
Russian Federation
References
1. Годжелло Э.А., Хрусталева М.В., Галлингер Ю.И. [и др.]. Выбор способа эндоскопического протезирования бластоматозных поражений пищевода, кардии и пищеводных анастомозов саморасправляющимися стентами // Вестник хирургической гастроэнтерологии. 2011. № 2. С. 14-24
2. Королев М.П., Федотов Л.Е., Смирнов А.А., Оглоблин А.Л. Эндоскопическое стентирование стенозирующих заболеваний пищевода: материалы 14-й Российской гастроэнтерологической недели // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2008. № 5. С. 164-166
3. Соколов В.В., Филоненко Е.В., Карпова Е.С. Эндоскопическое протезирование при злокачественной стриктуре пищевода // Эндоскопическое протезирование: сб. тезисов симпозиума. М., 2006. С. 63-69
4. Состояние онкологической помощи населению России в 2010 году / под ред. В.И. Чиссова [и др.]. М.: МНИОИ им.П.А. Герцена. 2011. 188 с
5. Hatogai K., Yano T., Kojima T. [et al.]. Salvage photodynamic therapy for local failure after chemoradiotherapy for esophageal squamous cell carcinoma // Gastrointest. Endosc. 2016. Vol. 83. P.1130-1139.
6. Hu Shaoshan, Zhan Qi, Yue Wu. The inhibiting effect of photodynamic therapy and novel recombinant human endostatin on the in vivo growth of U251 human glioma xenografts // Pacific Medical Journal. 2013. No. 4. P 67-71.
7. Hyeon Y.Y., Young K.Ch., Hye J.Ch., Chan S.Sh. Role of photodynamic therapy in the palliation of obstructing esophageal cancer // Korean J. Intern. Med. 2012. Vol. 27, No. 3. P 278-284. doi: 10.3904/kjim.2012.27.3.278
8. Lee H.H., Choi M.G., Hasan T. Application of photodynamic therapy in gastrointestinal disorders: an outdated or re-emerging technique? // Korean J. Intern. Med. 2017. Vol. 32, No. 1. P 1-10. doi: 10.3904/kjim.2016. 200.Review
9. Mangiavillano B., Pagano N., Arena M. [et al.]. Role of stenting in gastrointestinal benign and malignant diseases // World J. Gastrointest. Endosc. 2015. Vol. 16, No. 7 (5). P 460-480. doi: 10.4253/wjge.v7.i5.460.Review
10. McCaughan J.S., Photodynamic therapy for obstructive esophageal malignancies // Diagn. Ther. Endosc.1999. Vol. 5. P. 167-174.
11. Muto M., Yano T., Photodynamic therapy for local recurrence of esophageal cancer after chemoradiotherapy // Ап To Kagaku Ryoho. 2016. Vol. 43, No. 7. P. 1053-1057
12. Pantling A.Z., Gossage J.A., Mamidanna R. [et al.]. Outcomes from chemoradiotherapy for patients with esophageal cancer // Dis. Esophagus. 2011. Vol. 24. P 172-176.
13. Rupinski M., Zagorowicz E., Regula J. [et al.]. Randomized comparison of three palliative regimens including brachytherapy, photodynamic therapy, and APC in patients with malignant dysphagia (CONSORT 1a) (Revised II) // Am. J. Gastroenterol. 2011. Vol. 106. P. 1612-1620.
14. Tanaka T., Matono S., Nagano T. [et al.]. Photodynamic therapy for large superficial squamous cell carcinoma of the esophagus // Gastrointest Endosc. 2011. Vol. 73. P 1-6.
15. Yano T., Muto M., Minashi K. [et al.] Long-term results of salvage photodynamic therapy for patients with local failure after chemoradiotherapy for esophageal squamous cell carcinoma // Endoscopy. 2011. Vol. 43. P 657-663.
Review
For citations:
Tumanina A.N., Polezhaev A.A. Photodynamic therapy in the treatment of locally advanced esophageal cancer. Pacific Medical Journal. 2017;(3):75-76. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2017.3.75-77
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