NITROOXIDEERGIC PROCESSES AT MALABSORPTION SYNDROME IN CHILDREN WITH MUCOVISCIDOSIS
Abstract
The nitric oxide-ergic processes in intestinal mucous cells in 19 children in the age 2 months — 14 years with intestinal mucoviscidosis were evaluated. Upper GI endoscopy was done by «shortest pass» method with the subsequent biopsy for morphological and hystochemical analyses. The analysis of the received data has proved the presence of the nitroxidesynthase expression in intestinal cells in all patients which expressiveness was maximal in the presence of intestinal syndrome.
About the Authors
T. A. ShumatovaRussian Federation
O. B. Baranova
Russian Federation
S. N. Shishchatskaya
Russian Federation
Ya. E. Pavlova
Russian Federation
F. F. Antonenko
Russian Federation
References
1. Аруин Л.И. // Вестник РАМН. - 1994. - № 5.- С. 32-37.
2. Ванин А.Ф. // Вестник РАМН. - 2000. - № 4.- С. 3-5.
3. Гершман Г.Б., Боксер В.О. // Вопросы охраны материнства и детства. — 1987. — Т. 32, №7. — С. 20—24.
4. Детская гастроэнтерология (избранные главы) / под ред. А.А. Баранова, Е.В. Климанской, Г.В. Римарчук. — М.: Медицина, 2002.
5. Капранов Н.И., Шабалова Л.А., Каширская Н.Ю. Муковисцидоз (современные достижения и проблемы) : методические рекомендации. — М. : Медпрактика, 2001.
6. Фролькис А.В. Энтеральная недостаточность. — СПб.: Фолиант, 2003.
7. Bebok Z., Varga K., Hicks J.K. // J. ВЫ. Chem. - 2002. - Vol. 22. -P. 1215-1228.
8. Hope B. T., Michael G.J., Knigge K.M. // Proc. Natl. Acad. Sci. USA. - 1991. - No. 88. - P. 2811-2814.
9. Lee E.L., Feldman M. // Gastrointestinal Endoscopy Clinics of North America. - 2002. - Vol. 10, No. 4. - P. 669-712.
10. Wapnir R.A., Teichberg S.//J. Nutr. Biochem. - 2002. - Vol. 13, № 4. - Р. 190-199.
11. Morrissey B., Schilling К. //Arch. Biochem. Biophys. — 2002. - Vol. 406, No. 1. - P. 33-42.
Review
For citations:
Shumatova T.A., Baranova O.B., Shishchatskaya S.N., Pavlova Ya.E., Antonenko F.F. NITROOXIDEERGIC PROCESSES AT MALABSORPTION SYNDROME IN CHILDREN WITH MUCOVISCIDOSIS. Pacific Medical Journal. 2005;(3):73-75. (In Russ.)