DYNAMICS OF ADAPTIVE HORMONES CONCENTRATION DURING TREATMENT OF WOMEN WITH INFLAMMATORY DISEASES IN SMALL PELVIS

Abstract

The authors have examined 90 patients aged 17—36 suffering from non-specific inflammatory diseases of uterus and uterine appendages, including 28 women with acute me- troendometritis, 30 women with acute metroendometritis complicated by salpingo-oophoritis, and 32 women with exacerbation of chronic salpingo-oophoritis. When arriving in and discharging from the in-patient department, all patients were examined for thyrotrophic hormone, triiodothyronine, tetraiodothyronine, and cortisol in the blood serum. Changing concentrations of cortisol and thyrotrophic hormone under the conditions of acute endometritis evidenced the most favourable clinical course and outcome, while an abrupt increase of glucocorticoids and thyrotrophic hormone in the blood of patients suffering from complicated metroendometritis had adverse effect on the cellular and humoral immunity activity and resulted in more severe clinical course of this inflammatory disease. The patients suffering from exacerbation of chronic salpingo-oophoritis had moderately increased concentration of cortisol in blood that appeared to be insufficient to intensify inflammatory reaction and, therefore, to activate restoration.