ANTIPEROXID EFFECTS OF EXTRACT FROM STICHOPUS JAPONICUS
Abstract
Increased content of the lipid peroxidation products and reduced integral antiradical activity in liver tissue were found in experimental mice and rats with induced stress hypodynamia as well as in pilot rats with modeled acute carbon tetrachloride-induced hepatitis or liver fibrosis which were caused by combined administration of carbon tetrachloride and ethanol for one month. Preventive administration of an ethanol extract of stichopus to rats exerted antistress and antioxidant effects similar to the preparation of comparison silibinine.
About the Authors
A. V. Kropotov
Vladivostok State Medical University; Pacific Oceanological Institute Far East Branch of Russian Academy of Sciences (Vladivostok)
Russian Federation
Russian Federation
V. P. Chelomin
Vladivostok State Medical University; Pacific Oceanological Institute Far East Branch of Russian Academy of Sciences (Vladivostok)
Russian Federation
Russian Federation
N. V. Plaksen
Vladivostok State Medical University; Pacific Oceanological Institute Far East Branch of Russian Academy of Sciences (Vladivostok)
Russian Federation
Russian Federation
N. S. Khilchenko
Vladivostok State Medical University; Pacific Oceanological Institute Far East Branch of Russian Academy of Sciences (Vladivostok)
Russian Federation
Russian Federation
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Review
For citations:
Kropotov A.V., Chelomin V.P., Plaksen N.V., Khilchenko N.S. ANTIPEROXID EFFECTS OF EXTRACT FROM STICHOPUS JAPONICUS. Pacific Medical Journal. 2004;(3):18-20. (In Russ.)
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