Preview

Pacific Medical Journal

Advanced search

CO-LOCALIZATION OF SEROTONIN AND NITROOXIDESYNTHASE IN NEURONS OF SUBCORTICAL WHITE SUBSTANCE OF HUMAN BRAIN

Abstract

Localization of neuronal nitrooxidesynthase, serotonin and NADPH-diaphorase has been examined in cerebral cortex of fetuses (26-28 weeks), newborns and adults. In the subcortical white substance, as is shown, there is a nitroxydergic neuron population, a number and activity of which are unequal at different stages of neuroontogenesis. In an antenatal period a part of the nitroxydergic neurons synthesizes the serotonin and forms the neurovascular bonds.

About the Authors

S. V. Khrulev
Vladivostok State Medical University
Russian Federation


I. V. Duizen
Vladivostok State Medical University
Russian Federation


References

1. Дюйзен И.В., Калиниченко С.Г., Охотин В.Е., Мотавкин П.А.// Морфология. — 1998. — Т. 113, вып. 1. - С. 47-51.

2. Нейроонтогенез: Серия «Проблемы биологии развития» — М.: Наука, 1985.

3. Охотин В.Е., Калиниченко С.Г.// Морфология. — 2002. - Т. 121, вып. 1. - С. 7-26.

4. Ang L.C., Shul D.D.//Brain Res. - 1995. - Vol. 674. - P. 329-335.

5. Judas M., Sestan N., Kostovic I.//Microsc. Res. Tech. — 1999. - Vol. 45. - P. 401-419.

6. Kostovic I., Rakic P.//J. Neurocytol. - 1980. - Vol. 9. - P. 219-242.

7. Marin-Padilla M.//Cerebral cortex. — Vol.7: Development and maturation of cerebral cortex. — New York: Plenum Press, 1988. - P. 1-34.

8. Mizukawa K., Vincent S.R., McGeer P.L., McGeer E.G.// Brain Res. - 1988. - Vol. 461. - P. 274-281.

9. Prast H., Athineos P.//Progr. Neurobiol. - 2001. - Vol. 64, No. 1.-P. 51-68.

10. Valverde F., Facal-Valverde M.V.//J. Сomp. Neurol. — 1988. - Vol. 269. - P. 168-192.

11. Vincent S.R., Kimura H.// Neuroscience. — 1992. — Vol. 46.- P. 755-784.


Review

For citations:


Khrulev S.V., Duizen I.V. CO-LOCALIZATION OF SEROTONIN AND NITROOXIDESYNTHASE IN NEURONS OF SUBCORTICAL WHITE SUBSTANCE OF HUMAN BRAIN. Pacific Medical Journal. 2004;(2):23-26. (In Russ.)

Views: 233


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1609-1175 (Print)