IMPORTANCE OF CYTOKINE STATE IN RESEARCHING INTO THE IMMUNOPATHOGENESIS OF INFECTIOUS DISEASES
Abstract
The paper provides data on the researches into the cytokine state under hemorrhagic fever with renal syndrome, chronic viral hepatitis type C, ixode tickborreliosis, and nosocomial pneumonias. The authors have inquired into the content of proinflammatory and anti-inflammatory cytokines at system and local levels (in blood serum, bronchoalveolar fluid supernatants, liver homogenate, expired air condensate). According to the findings, infectious disease pathogens are initiators of the infectious process, and the so-called «direction» in pathogeny belongs to organism immune response that detects the severity, clinical course and form of the disease.
About the Authors
V. A. Ivanis
Vladivostok State Medical University
Russian Federation
Russian Federation
E. V. Markelova
Vladivostok State Medical University
Russian Federation
Russian Federation
L. F. Sklyar
Vladivostok State Medical University
Russian Federation
Russian Federation
A. I. Simakova
Vladivostok State Medical University
Russian Federation
Russian Federation
N. V. Mandrakova
Vladivostok State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Ivanis V.A., Markelova E.V., Sklyar L.F., Simakova A.I., Mandrakova N.V. IMPORTANCE OF CYTOKINE STATE IN RESEARCHING INTO THE IMMUNOPATHOGENESIS OF INFECTIOUS DISEASES. Pacific Medical Journal. 2004;(2):36-39. (In Russ.)
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