NITRIC OXIDE PRODUCTION IN MUCOUS MEMBRANE OF SMALL INTESTINES OF CHILDREN WITH INTESTINAL MALABSORPTION SYNDROME

Abstract

The authors have examined 34 children aged from three months to nine years with celiac disease (16) and lac-tase deficiency (18). They have detected nitroxide-producing function of mucous membrane of small intestines. The findings are the evidence of the participation of nitroxidergic mechanisms in the intestinal absorption processes. The peak level of nitroxide synthesis has coincided with the most apparent clinical presentations of the malabsorption: as the intestinal syndrome intensity decreased, nitroxide synthase activity of enterocytes went down.