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Pacific Medical Journal

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Interleukin-17 family in atopy and allergic diseases

https://doi.org/10.17238/PmJ1609-1175.2018.2.15-20

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Abstract

The review provides the information about the features of molecular and genetic mechanisms and biological effects of Interleukin-17 family members in immunopathogenesis of atopy and design of allergic pathology. The correlation of Interleukin-17 family members in the system of cytokine initial regulation, development and course of allergic diseases was analyzed. The significance of genetic predictors and imbalance of cytokine profile of Interleukin-17 family is discussed to foresee the design of endo- and phenotypic features of the course of bronchial asthma, allergic rhinitis, and atopic dermatitis.

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Prosekova E.V., Turyanskaya A.I., Dolgopolov M.S. Interleukin-17 family in atopy and allergic diseases. Pacific Medical Journal. 2018;(2):15-20. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2018.2.15-20

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ISSN 1609-1175 (Print)