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Interleukin-17 family in atopy and allergic diseases

https://doi.org/10.17238/PmJ1609-1175.2018.2.15-20

Abstract

The review provides the information about the features of molecular and genetic mechanisms and biological effects of Interleukin-17 family members in immunopathogenesis of atopy and design of allergic pathology. The correlation of Interleukin-17 family members in the system of cytokine initial regulation, development and course of allergic diseases was analyzed. The significance of genetic predictors and imbalance of cytokine profile of Interleukin-17 family is discussed to foresee the design of endo- and phenotypic features of the course of bronchial asthma, allergic rhinitis, and atopic dermatitis.

About the Authors

E. V. Prosekova
Pacific State Medical University
Russian Federation


A. I. Turyanskaya
Pacific State Medical University
Russian Federation


M. S. Dolgopolov
Pacific State Medical University
Russian Federation


References

1. Кудрявцев И.В., Борисов А.Г., Волков А.Е. [и др.]. Анализ уровня экспрессии CD56 и CD57 цитотоксическими Т-лимфоцитами различного уровня дифференцировки // Тихоокеанский медицинский журнал. 2015. № 2. С. 30-35

2. Курбачева О.М., Павлова К.С. Фенотипы и эндотипы бронхиальной астмы: от патогенеза и клинической картины к выбору терапии // Российский аллергологический журнал. 2013. № 1. С. 15-24

3. Agache I., Akdis C., Jutel M., Virchow J.C. Untangling asthma phenotypes and endotypes // Allergy. 2012. Vol. 67. Р. 835-846.

4. Agache I., Ciobanu C., Agache C., Anghel M. Increased serum IL-17 is an independent risk factor for severe asthma // Respiratory Medicine. 2010. Vol. 104. Р. 1131-1137.

5. Aggarwal S., Ghilardi N., Xie M.H. [et al.]. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 // J. Biol. Chem. 2003. Vol. 278, No. 3. Р. 1910-1914.

6. Akdis C.A., Agache I. The underlying mechanisms in allergy // EAACI Global Atlas of Allergy. Zurich: European Academy of Allergy and Clinical Immunology. 2014. Р. 39-42.

7. Al-Muhsen S., Johnson J.R., Hamid Q. Remodeling in asthma // J. Allergy Clin. Immunol. 2011. Vol. 128, No. 3. P. 451-462.

8. Brasier A.R., Sundar V., Ju H. [et al.]. Predicting intermediate phenotypes in asthma using bronchoalveolar lavage-derived cytokines // Clinical and Translational Science. 2010. Vol. 3, No. 4. Р. 147-157.

9. Chen Z., Laurence A., Kanno Y. [et al.]. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells // Proc. Natl. Acad. Sci. U.S.A. 2006. Vol. 103, No. 21. P. 8137-8142.

10. Commins S., Borish L., Steinke J. Immunologic messenger molecules: Cytokines, interferons and chemokines // J. Allergy Clin. Immunol. 2010. Vol. 125, No. 2. Р. 53-72.

11. Cosmi L., Liotta F., Maggi E., Romagnani S., Annunziato F. Th17-cells: New players in asthma pathogenesis // Allergy. 2011. Vol. 66. P. 989-998.

12. Duerr R., Taylor K., Brant S. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene // Science. 2006. Vol. 2. Р. 61-63.

13. Doe C., Bafahel M., Siddiqui S. [et al.]. Expression ofthe T helper 17-associated cytokines M.H-17A and M.H-17F in asthma and COPD // Chest. 2010. Vol. 138, No. 5. P. 1140-1147.

14. Du J., Han J.-Ch., Zhang Y.-J. [et al.]. Single-nucleotide polymorphisms of IL-17 gene are associated with asthma susceptibility in an Asian population // Med. Sci. Monit. 2016. Vol. 22. P. 780-787.

15. Gaffen S.L. Structure and signalling in the ИЛ-17 receptor family // Nat. Rev. Immunol. 2009. Vol. 9, No. 8. Р. 556-567.

16. Hayashida S., Uchi H., Moroi Y., Furue M. Decrease in circulating Th17 cells correlates with increased levels of CCL17, IgE and eosinophils in atopic dermatitis // J. Dermatol. Sci. 2011. Vol. 61, No. 3. Р. 180-186.

17. Hirohisa Saito. Innate lymphoid cells // EAACI Global Atlas of Allergy. Zurich: European Academy of Allergy and Clinical Immunology, 2014. Р. 50-52.

18. Holgate S.T. Innate and adaptive immune responses in asthma // Nat. Med. 2012. Vol. 18. P. 673-683.

19. Ivanov I.I., McKenzie B.S., Zhou L. [et al.] The orphan nuclear receptor ROR-y directs the differentiation program of proinflammatory IL-17+ T helper cells // Cell. 2006. Vol. 126, No. 6. P. 1121-1133.

20. Kawaguchi M., Kokubu F., Fujita J. [et al.]. Role of interleukin-17F in asthma // Inflamm. Allergy Drug. Targets. 2009. Vol. 8, No. 5. P. 383-389.

21. Kawaguchi M., Takahashi D., Hizawa N. [et al.]. IL-17F sequence variant (His161 Arg) is associated with protection against astma and antagonizes wild-type IL-17F activity // J. Allergy Clin. Immunol. 2006. Vol. 117, No. 4. P. 795-801.

22. Kellner H. Targeting interleukin-17 in patients with active rheumatoid arthritis: rationale and clinical potential // Ther. Adv. Musculoskeletal. Dis. 2013. Vol. 5, No. 3. P. 141-152.

23. Kenna TJ, Brown MA. The role of IL-17-secreting mast cells in inflammatory joint disease // Nat. Rev. Rheumatol. 2012. Vol. 9, No. 6. P. 375-379.

24. Kimura A, Kishimoto T. IL 6: Regulator of Treg/Th17 balance // Eur. J. Immunol. 2010. Vol. 40, No. 7. Р.1830-1835.

25. Koga C., Kabashima K., Shiraishi N. [et al.]. Possible pathogenic role of Th17 cells for atopic dermatitis // J. Invest. Dermatol. 2008. Vol. 128. Р. 2625-2630.

26. Kolls J.K., Lindén A. Interleukin-17 family members and inflammation // Immunity. 2004. Vol. 21, No. 4. P 467-476.

27. Lajoie S., Lewkowich I.P, Suzuki Y. [et al.]. Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma // Nature Immunology. 2010. Vol. 11, No. 10. P. 928-935.

28. Ley K., Smith E., Stark M.A. IL-17A-producing neutrophil-regulatory Th lymphocytes // Immunol. Res. 2006. Vol. 34, No. 3. P. 229-242.

29. Louten J., Boniface K., de Waal Malefyt R. Development and function of TH17 cells in health and disease // J. Allergy Clin. Immunol. 2009. Vol. 123, No. 5. P1004-1011.

30. Mangan P, Harrington L., O’Quinn D. Transforming growth factor-beta induces development of the T(H)17 lineage // Nature. 2006. Vol. 7. Р. 32-34.

31. Martin D.A., Towne J.E., Kricorian G. [et al.]. The emerging role of IL-17 in the pathogeneasis of psoriasis: preclinical and clinical findings // J. Invest. Dermatol. 2013. Vol. 133, No. 1. Р 17-26.

32. Miossec P IL-17 and Th17 cells in human inflammatory diseases // Microbes Infect. 2009. Vol. 11, No. 5. Р 625-630.

33. Miossec P., Kolls J. K. Targeting IL-17 and Th17 cells in chronic inflammation // Nature reviews. 2012. Vol. 11. P. 763-776.

34. Moseley T.A., Haudenschild D.R., Rose L., Reddi A.H. Interleukin-17 family and IL-17 receptors // Cytokine Growth Factor Rev. 2003. Vol. 14, No. 2. P. 155-174.

35. Mübeccel A. The pathogenesis of asthma // Global Atlas of Asthma. Zurich: European Academy of Allergy and Clinical Immunology, 2013. Р 28-30.

36. Nembrini C., Marsland B.J., Kopf M. IL-17-producing T cells in lung immunity and inflammation // J. Allergy Clin. Immunol. 2009. Vol. 123. P 986-994.

37. Onishi R.M., Gaffen S.L. Interleukin-17 and its target genes: Mechanisms of interleukin-17 function in disease // Immunology. 2010. Vol. 129, No. 3. Р311-321.

38. Papadopoulos N.G., Agache I., Bavbek S. [et al.]. Research needs in allergy: An EAACI position paper, in collaboration with EFA // Clin. Transl. Allergy. 2012. Vol. 2, No. 1. P 21.

39. Poulsen L.K. Cytokines and chemokines in allergic rhinitis // EAACI Global Atlas of Allergic Rhinitis and Chronic Rhinosinusitis. Zurich: European Academy of Allergy and Clinical Immunology, 2015. Р 29-31.

40. Poulsen L.K. Cytokines in allergy // EAACI Global Atlas of Allergy. Zurich: European Academy of Allergy and Clinical Immunology, 2014. Р. 69-70.

41. Qian F., Zhang Q., Zhou L. [et al.]. Association between polymorphisms in IL17F and male asthma in a Chinese population // J. Investig. Allergol. Clin. Immunol. 2012. Vol. 22, No. 4. P. 257-263.

42. Qu N., Xu M., Mizoguchi I. [et al.]. Pivotal roles of T-helper 17-telated cytokines, IL-17, IL-22, and IL-23, in inflammatory diseases // Clin. Devel. Immunol. 2013. PMID: 23956763.

43. Seoung J.P, Lee Y.C. Interleukin-17 regulation: an attractive therapeutic approach for asthma // Respiratory Research. 2010. Vol. 11. P. 78.

44. Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage // Nature Med. 2007. Vol. 13. Р 136-140.

45. Triggiani M., Jutel M., Knol E. The underlying mechanisms of asthma // EAACI Global Atlas of Asthma. Zurich: European Academy of Allergy and Clinical Immunology, 2013. Р 31-33.

46. Van Drunen C.M. The role of T- and B-lymphocytes in allergic disease // Global atlas of allergic rhinitis and chronic rhinosinusitis: European Academy of Allergy and Clinical Immunology, 2015. P 27-28.

47. Veldhoen M., Hocking R.J., Atkins C.J. [et al.]. TGF beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells // Immunity. 2006. Vol. 24, No. 2. P. 179-189.

48. Yan J., Zaichun D., Chao C., Longxiang L. IL-17 polymorphisms and asthma risk: a meta-analysis of11 single nucleotide polymorphisms // Journal of Asthma. 2015. Vol. 52, No. 10. P. 981-988.

49. Zhu M., Wang T., Chen R. [et al.]. Association between interleukin-17a gene polymorphisms and asthma risk: A meta-analysis // Asian Pacific Journal of Allergy and Immunology. 2016. Vol. 34, No. 2. P. 115-123.

50. Zhu S., Qian Y. IL-17/IL-17 receptor system in autoimmune disease: Mechanisms and therapeutic potential // Clin. Sci. 2012. Vol. 122, No. 11. Р. 487-511.


Review

For citations:


Prosekova E.V., Turyanskaya A.I., Dolgopolov M.S. Interleukin-17 family in atopy and allergic diseases. Pacific Medical Journal. 2018;(2):15-20. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2018.2.15-20

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ISSN 1609-1175 (Print)