Post-injection necrosis of femoral soft tissues induced by diclofenac, nonsteroidal anti-inflammatory drug (clinical case)
https://doi.org/10.34215/1609-1175-2023-2-86-88
Abstract
Nikolau syndrome is a rare post-injection complication with unclear etiology and pathogenesis, characterized by the development of acute local pain syndrome, localized erythematous rash, livedoid and hemorrhagic skin lesions with foci of ischemic necrosis. The paper presents a clinical case of Nikolau syndrome induced by intramuscular administration of diclofenac solution as an analgesic after hip replacement. The analysis of the causes, clinical picture and stages of treatment of post-injection complication was carried out.
About the Authors
V. A. Atoian
Far Eastern Federal University
Russian Federation
Russian Federation
Varsik A. Atoian - PhD student of the Department of Internal Diseases.
School of Medicine, building M, 10 Ajax village, Russian Island, Vladivostok 690002
M. F. Fadeev
Far Eastern Federal University
Russian Federation
Russian Federation
Vladivostok
A. S. Zolotov
Far Eastern Federal University
Russian Federation
Russian Federation
Vladivostok
E. A. Zinkova
Far Eastern Federal University
Russian Federation
Russian Federation
Vladivostok
B. I. Geltser
Far Eastern Federal University
Russian Federation
Russian Federation
Vladivostok
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Review
For citations:
Atoian V.A., Fadeev M.F., Zolotov A.S., Zinkova E.A., Geltser B.I. Post-injection necrosis of femoral soft tissues induced by diclofenac, nonsteroidal anti-inflammatory drug (clinical case). Pacific Medical Journal. 2023;(2):86-88. (In Russ.) https://doi.org/10.34215/1609-1175-2023-2-86-88
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