THE ROLE OF ACINETOBACTER BAUMANNII STRAINS IN THE DEVELOPMENT OF SEPTIC COMPLICATIONS IN CASE OF BURN INJURY
https://doi.org/10.17238/PmJ1609-1175.2019.3.18-23
Abstract
We have analyzed literature data related to contagion issue and Acinetobacter baumannii strains circulation in hospital conditions; we have considered questions of development of resistance to antibiotics, invasion factors and quorum sensing that enables them to bear significant changes of environmental conditions such as drying and cleaning with detergents. Carbapenems have before used as a drug of choice to treat infections caused by A. baumannii. However resistance improvement of bacterium to this group of antibacterial drugs caused by β-lactamases of groups B and D makes further therapy with carbapenems senseless. We have assessed the role of process of formation of biofilms by A. baumannii strains, which facilitate bacteria persistence in human body and serve as important virulence factor. Organizing effective and dynamic infection control in resuscitation and intensive care departments is considered to be an important trend in quality management and healthcare services.
About the Authors
T. D. Fomicheva
Pacific State Medical University
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
Yu. E. Skurikhina
Pacific State Medical University
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
S. A. Sotnichenko
Far East Medical Center FMBA
Russian Federation
161 100 Years of Vladivostok Ave. Vladivostok 690000 Russian Federation
Russian Federation
161 100 Years of Vladivostok Ave. Vladivostok 690000 Russian Federation
P. A. Griban
Far East Medical Center FMBA
Russian Federation
161 100 Years of Vladivostok Ave. Vladivostok 690000 Russian Federation
Russian Federation
161 100 Years of Vladivostok Ave. Vladivostok 690000 Russian Federation
V. V. Fedorets
Pacific State Medical University
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
M. V. Tymoshenko
Pacific State Medical University
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
R. R. Ayvazian
Pacific State Medical University
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
Russian Federation
2 Ostryakova Ave. Vladivostok 90002 Russian Federation
References
1. Atakishizade S.A. Sensitivity of nosocomial strains of bacteria of the genus Acinetobacter to some antibiotics in the multi-profile hospital in Baku // Pediatric Infections. 2018. No. 3. P. 62–63.
2. Atakishizade S.A. Sensitivity of nosocomial strains of bacteria of the genus Acinetobacter to some antibiotics in the multi-profile hospital in Baku // Pediatric Infections. 2018. No. 3. P. 62–63.
3. Vorobieva O.N., Chelysheva G.M., Doshchitsina A.S. [et al.]. Resistance of pathogens of burn disease to antibiotics // Modern Problems of Medical Microbiology. Saint Petersburg, 2007. P. 165–167.
4. Vorobieva O.N., Chelysheva G.M., Doshchitsina A.S. [et al.]. Resistance of pathogens of burn disease to antibiotics // Modern Problems of Medical Microbiology. Saint Petersburg, 2007. P. 165–167.
5. Goncharov A.E. Epidemiological features of purulent-septic infections caused by Acinetobacter baumannii and Preudomonas aeruginosa in the burn-through intensive care unit: Thesis for the degree of candidate of medical sciences. Saint Petersburg, 2005. 151 p.
6. Goncharov A.E. Epidemiological features of purulent-septic infections caused by Acinetobacter baumannii and Preudomonas aeruginosa in the burn-through intensive care unit: Thesis for the degree of candidate of medical sciences. Saint Petersburg, 2005. 151 p.
7. Gorbich Yu.L., Karpov I.A. The value of adequate empirical antibacterial therapy for nosocomial infections caused by Acinetobacter baumannii // Clin. Microbiol. Antimicrob. Chemother. 2012. Vol. 14, No. 1. P. 67–73.
8. Gorbich Yu.L., Karpov I.A. The value of adequate empirical antibacterial therapy for nosocomial infections caused by Acinetobacter baumannii // Clin. Microbiol. Antimicrob. Chemother. 2012. Vol. 14, No. 1. P. 67–73.
9. Gordinskaya N.A. Sabirova E.V., Abramova N.V. Karbapenemresistant gram-negative bacteria in the structure of wound burn microflora // Medical Almanac. 2018. No. 4. P. 34–37.
10. Gordinskaya N.A. Sabirova E.V., Abramova N.V. Karbapenemresistant gram-negative bacteria in the structure of wound burn microflora // Medical Almanac. 2018. No. 4. P. 34–37.
11. Zhilina S.V., Mironov A.Yu., Polikarpova S.V. Acinetobacter in infections of the skin and soft tissues // Kursk Scientific and Practical Journal “Man and His Health”. 2007. No. 4. P. 45–56.
12. Zhilina S.V., Mironov A.Yu., Polikarpova S.V. Acinetobacter in infections of the skin and soft tissues // Kursk Scientific and Practical Journal “Man and His Health”. 2007. No. 4. P. 45–56.
13. Zubkov M.N. Non-fermenting bacteria Acinetobacter spp.: Taxonomy and classification, characterization, clinical significance, identification, antibiotic resistance // Infectsii i antimikrobnaya terapiya. 2003. No. 2. P. 18–26.
14. Zubkov M.N. Non-fermenting bacteria Acinetobacter spp.: Taxonomy and classification, characterization, clinical significance, identification, antibiotic resistance // Infectsii i antimikrobnaya terapiya. 2003. No. 2. P. 18–26.
15. Krylov KM, Yafaev R.Kh., Demakov V.A. [et al.]. Genetic diversity of Acinetobacter baumannii in the department of burns resuscitation // Journal of Microbiology, Epidemiology and Immunology. 2006. No. 2. P. 25–30.
16. Krylov KM, Yafaev R.Kh., Demakov V.A. [et al.]. Genetic diversity of Acinetobacter baumannii in the department of burns resuscitation // Journal of Microbiology, Epidemiology and Immunology. 2006. No. 2. P. 25–30.
17. Prisakar V.I., Berdeu I.S., Spataru D.Yu. The results of the evaluation of microbial antibiotic resistance in the conditions of the Republic of Moldova // Medical Almanac. 2018. No. 4. P. 31–34.
18. Prisakar V.I., Berdeu I.S., Spataru D.Yu. The results of the evaluation of microbial antibiotic resistance in the conditions of the Republic of Moldova // Medical Almanac. 2018. No. 4. P. 31–34.
19. Satosova N.V. Epidemiology and prevention of blood flow infections in the department of burn resuscitation and intensive therapy: Thesis for the degree of candidate of medical sciences. Saint Petersburg, 2012. 144 p.
20. Satosova N.V. Epidemiology and prevention of blood flow infections in the department of burn resuscitation and intensive therapy: Thesis for the degree of candidate of medical sciences. Saint Petersburg, 2012. 144 p.
21. Satosova N.V., Krylov K.M., Zueva L.P. [et al.]. The results of epidemiological monitoring of bloodstream infections in the intensive care unit and intensive care for victims with severe thermal injury // Hematology Bulletin. 2010. Vol. VI, No. 1. P. 61.
22. Satosova N.V., Krylov K.M., Zueva L.P. [et al.]. The results of epidemiological monitoring of bloodstream infections in the intensive care unit and intensive care for victims with severe thermal injury // Hematology Bulletin. 2010. Vol. VI, No. 1. P. 61.
23. Skurikhina Yu.E., Ibragimova T.D., Skurikhina L.A. [et al.]. Molecular epidemiological analysis of Acinetobacter baumannii strains isolated from patients with a burn injury // Modern Technologies in Medicine. 2016. Vol. 8. No. 1. P. 134–139.
24. Skurikhina Yu.E., Ibragimova T.D., Skurikhina L.A. [et al.]. Molecular epidemiological analysis of Acinetobacter baumannii strains isolated from patients with a burn injury // Modern Technologies in Medicine. 2016. Vol. 8. No. 1. P. 134–139.
25. Skurikhina Yu.E. Prushinsky A.P., Zavalina D.E. The prevalence of purulent-septic infections in the departments of children's multidisciplinary hospital // Far Eastern Journal of Infectious Pathology. 2017. No. 32. P. 58–67.
26. Skurikhina Yu.E. Prushinsky A.P., Zavalina D.E. The prevalence of purulent-septic infections in the departments of children's multidisciplinary hospital // Far Eastern Journal of Infectious Pathology. 2017. No. 32. P. 58–67.
27. Skurikhina Yu.E., Turkutyukov V.B. Microbiological features of non-fermentative gram-negative bacteria and their influence on the development of the epidemic process of infections associated with the provision of medical care // Pacific Medical Journal. 2016. No. 3, Suppl. P. 111
28. Skurikhina Yu.E., Turkutyukov V.B. Microbiological features of non-fermentative gram-negative bacteria and their influence on the development of the epidemic process of infections associated with the provision of medical care // Pacific Medical Journal. 2016. No. 3, Suppl. P. 111
29. Tapalsky D.V., Bonda N.A. Acinetobacter baumannii: prevalence, spectrum and dynamics of antibiotic resistance, sensitivity to combinations of antibiotics // Journal of Grodno State Medical University. 2018. Vol. 16, No. 3. P. 286–291
30. Tapalsky D.V., Bonda N.A. Acinetobacter baumannii: prevalence, spectrum and dynamics of antibiotic resistance, sensitivity to combinations of antibiotics // Journal of Grodno State Medical University. 2018. Vol. 16, No. 3. P. 286–291
31. Tarasov A.E. Immunological aspects of burn disease in the clinic and experiment: Thesis for the degree of candidate of medical sciences. Vladivostok, 2009. 130 p.
32. Tarasov A.E. Immunological aspects of burn disease in the clinic and experiment: Thesis for the degree of candidate of medical sciences. Vladivostok, 2009. 130 p.
33. Tets V.V., Zaslavskaya N.V. The effectiveness of antibiotics on bacteria in biofilms // Journal of Microbiology, Epidemiology and Immunobiology. 2005. No. 5. P. 24–26.
34. Tets V.V., Zaslavskaya N.V. The effectiveness of antibiotics on bacteria in biofilms // Journal of Microbiology, Epidemiology and Immunobiology. 2005. No. 5. P. 24–26.
35. Turkutyukov V.B., Ibragimova T.D., Shmagunova E.V. Etiology of purulent-septic complications in a burn injury and monitoring the sensitivity of microorganisms to antibiotics // Journal of Microbiology, Epidemiology and Immunobiology. 2014. No. 2. P. 129.
36. Turkutyukov V.B., Ibragimova T.D., Shmagunova E.V. Etiology of purulent-septic complications in a burn injury and monitoring the sensitivity of microorganisms to antibiotics // Journal of Microbiology, Epidemiology and Immunobiology. 2014. No. 2. P. 129.
37. Fomicheva T.D., Turkutyukov V.B., Sotnichenko S.A. [et al.]. Microbiological monitoring in the system of epidemiological surveillance of purulent-septic infections with burn injury // Pacific Medical Journal, 2018. No. 3. P. 72–74.
38. Fomicheva T.D., Turkutyukov V.B., Sotnichenko S.A. [et al.]. Microbiological monitoring in the system of epidemiological surveillance of purulent-septic infections with burn injury // Pacific Medical Journal, 2018. No. 3. P. 72–74.
39. Shlyk I.V., Satosova N.V., Krylov K.M. [et al.]. Epidemiological monitoring in the department of burns resuscitation // Infections in Surgery. 2008. Vol. 6, No. 3. P. 23–27.
40. Shlyk I.V., Satosova N.V., Krylov K.M. [et al.]. Epidemiological monitoring in the department of burns resuscitation // Infections in Surgery. 2008. Vol. 6, No. 3. P. 23–27.
41. Acosta J., Merino M., Viedma E. Multidrug-resistant Acinetobacter baumanii harboring OXA-24 Carbapenemase, Spain // Emerg. Infect. Dis. 2011. Vol. 17, No. 6. P.1064–1067.
42. Acosta J., Merino M., Viedma E. Multidrug-resistant Acinetobacter baumanii harboring OXA-24 Carbapenemase, Spain // Emerg. Infect. Dis. 2011. Vol. 17, No. 6. P.1064–1067.
43. Al Atrouni A., Hamze, M., Jisr, T. [et al.]. Wide spread of OXA-23-producing carbapenem-resistant Acinetobacter baumannii belonging to clonal complex II in different hospitals in Lebanon // Int. J. Infect. Dis. 2016. Vol. 52. P. 29–36.
44. Al Atrouni A., Hamze, M., Jisr, T. [et al.]. Wide spread of OXA-23-producing carbapenem-resistant Acinetobacter baumannii belonging to clonal complex II in different hospitals in Lebanon // Int. J. Infect. Dis. 2016. Vol. 52. P. 29–36.
45. Al-Agamy M.H., Jeannot K., El-Mahdy T.S. [et al.]. First detection of ges-5 carbapenemase-producing Acinetobacter baumannii isolate // Microb. Drug Resist. 2016. doi: 10.1089/mdr.2016.0152
46. Al-Agamy M.H., Jeannot K., El-Mahdy T.S. [et al.]. First detection of ges-5 carbapenemase-producing Acinetobacter baumannii isolate // Microb. Drug Resist. 2016. doi: 10.1089/mdr.2016.0152
47. Aly M.M., Abu Alsoud N.M., Elrobh M.S. [et al.]. High prevalence of the PER-1 gene among carbapenem-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia // Eur. J. Clin. Microbiol. Infect. Dis. 2016. Vol. 35. P. 1759–1766.
48. Aly M.M., Abu Alsoud N.M., Elrobh M.S. [et al.]. High prevalence of the PER-1 gene among carbapenem-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia // Eur. J. Clin. Microbiol. Infect. Dis. 2016. Vol. 35. P. 1759–1766.
49. Babik J., Bodnarova L., Sopko K. [et al.]. Acinetobacter – serious danger for burn patients // Acta Chir. Plast. 2008. Vol. 50, No. 1. P. 27–32.
50. Babik J., Bodnarova L., Sopko K. [et al.]. Acinetobacter – serious danger for burn patients // Acta Chir. Plast. 2008. Vol. 50, No. 1. P. 27–32.
51. Bahador A., Farshadzadeh Z., Raoofian R. [et al.]. Association of virulence gene expression with colistin-resistance in Acinetobacter baumannii: Analysis of genotype, antimicrobial susceptibility, and biofilm formation // Annals of Clinical Microbiology and Antimicrobials. 2018. Vol. 17, No. 1. P. 24.
52. Bahador A., Farshadzadeh Z., Raoofian R. [et al.]. Association of virulence gene expression with colistin-resistance in Acinetobacter baumannii: Analysis of genotype, antimicrobial susceptibility, and biofilm formation // Annals of Clinical Microbiology and Antimicrobials. 2018. Vol. 17, No. 1. P. 24.
53. Bassetti M., Righi E., Esposito S. [et al.]. Drug treatment for multidrug-resistant Acinetobacter baumannii infections // Future Microbiol. 2008. Vol. 3, No. 6. P. 649–660.
54. Brahmi N., Biel Y., Kouraichi A. [et al.]. Evoluotion of resistance in Acinetobacter baumannii in Tunisian ICU after antibiotic therapy restriction // Crit. Сare. 2005. Vol. 9, Suppl. 1. P. 19.
55. Bassetti M., Righi E., Esposito S. [et al.]. Drug treatment for multidrug-resistant Acinetobacter baumannii infections // Future Microbiol. 2008. Vol. 3, No. 6. P. 649–660.
56. Carvalho K.R., D’Alincourt A., Carvalho-Assef A.P. [et al.]. Occurrence of blaOXA-23 gene in imipenem-susceptible Acinetobacter baumannii // Mem. Inst. Oswaldo Cruz, Rio de Janeiro. 2011. Vol. 106, No. 4. P. 505–506.
57. Brahmi N., Biel Y., Kouraichi A. [et al.]. Evoluotion of resistance in Acinetobacter baumannii in Tunisian ICU after antibiotic therapy restriction // Crit. Сare. 2005. Vol. 9, Suppl. 1. P. 19.
58. Chang-Ro Lee, Jung Hun Lee, Moonhee Park [et al.]. Biology of Acinetobacter baumannii: Pathogenesis, antibiotic resistance mechanisms, and prospective treatment options // Front. Cell. Infect. Microbiol. 2017. Vol. 7. Art. 55.
59. Carvalho K.R., D’Alincourt A., Carvalho-Assef A.P. [et al.]. Occurrence of blaOXA-23 gene in imipenem-susceptible Acinetobacter baumannii // Mem. Inst. Oswaldo Cruz, Rio de Janeiro. 2011. Vol. 106, No. 4. P. 505–506.
60. Chihi, H., Bonnin, R. A., Bourouis, A. [et al.]. GES-11-producing Acinetobacter baumannii clinical isolates from Tunisian hospitals: Long-term dissemination of GES-type carbapenemases in North Africa // J. Glob. Antimicrob. Resist. 2016. Vol. 5. P. 47–50.
61. Chang-Ro Lee, Jung Hun Lee, Moonhee Park [et al.]. Biology of Acinetobacter baumannii: Pathogenesis, antibiotic resistance mechanisms, and prospective treatment options // Front. Cell. Infect. Microbiol. 2017. Vol. 7. Art. 55.
62. Church D., Elsayed S., Reid O. [et al.]. Burn wound infections // Clin. Microbiol. Rev. 2006. Vol. 19, No. 2. P. 403–434.
63. Chihi, H., Bonnin, R. A., Bourouis, A. [et al.]. GES-11-producing Acinetobacter baumannii clinical isolates from Tunisian hospitals: Long-term dissemination of GES-type carbapenemases in North Africa // J. Glob. Antimicrob. Resist. 2016. Vol. 5. P. 47–50.
64. Cobrado L., Pinto Silva A., Pina-Vaz C. [et al.]. Effective disinfection of a burn unit after two cases of sepsis caused by multi-drugresistant Acinetobacter baumannii // Surg. Infect. 2018. Vol. 19, No. 5. P. 541–543.
65. Church D., Elsayed S., Reid O. [et al.]. Burn wound infections // Clin. Microbiol. Rev. 2006. Vol. 19, No. 2. P. 403–434.
66. Fluit, A. C., Maarten R., Visser A. [et al.]. Molecular detectionon of antimicrobial resistance // Clin. Microbiol. Rev. 2001. Vol. 14, No. 4. P. 836–871.
67. Cobrado L., Pinto Silva A., Pina-Vaz C. [et al.]. Effective disinfection of a burn unit after two cases of sepsis caused by multi-drugresistant Acinetobacter baumannii // Surg. Infect. 2018. Vol. 19, No. 5. P. 541–543.
68. Frikh M., Abdelhay L., Jalal K. [et al.]. Profile and antibiotic susceptibility of bacteria isolates in burn patients hospitalized in a Moroccan hospital: A cross-sectional study // Wounds: A Compendium of Clinical Research and Practice. 2018. Vol. 30, No. 4. P. 102–107.
69. Fluit, A. C., Maarten R., Visser A. [et al.]. Molecular detectionon of antimicrobial resistance // Clin. Microbiol. Rev. 2001. Vol. 14, No. 4. P. 836–871.
70. Gaddy J. Actis L. Regulation of Acinetobacter baumannii biofilm formation // Future Microbiol. 2009. Vol. 4. P. 273–278.
71. Frikh M., Abdelhay L., Jalal K. [et al.]. Profile and antibiotic susceptibility of bacteria isolates in burn patients hospitalized in a Moroccan hospital: A cross-sectional study // Wounds: A Compendium of Clinical Research and Practice. 2018. Vol. 30, No. 4. P. 102–107.
72. Mitchell J., Schwaber M., Cosgrove S. [et al.]. Fluoroquinolones protective against cephalosporin resistance in gram-negative nosocomial pathogens // Emerg. Infect. Dis. 2004. Vol. 10, No. 1. P. 94–98.
73. Gaddy J. Actis L. Regulation of Acinetobacter baumannii biofilm formation // Future Microbiol. 2009. Vol. 4. P. 273–278.
74. Mugnier P.D., Poirel L., Naas T. [et al.]. Worldwide dissemination of the blaOXA-23 carbapenemase gene of Acinetobacter baumannii // Emerg. Infect. Dis. 2010. Vol. 16, No. 1. P. 35–40.
75. Mitchell J., Schwaber M., Cosgrove S. [et al.]. Fluoroquinolones protective against cephalosporin resistance in gram-negative nosocomial pathogens // Emerg. Infect. Dis. 2004. Vol. 10, No. 1. P. 94–98.
76. Munier A., Biardb L., Legrandc M. [et al.]. Incidence, risk factors and outcome of multi-drug resistant Acinetobacter baumannii nosocomial infections during an outbreak in a burn unit // Int. J. Infect. Dis. 2019. Vol. 79. P. 179–184.
77. Mugnier P.D., Poirel L., Naas T. [et al.]. Worldwide dissemination of the blaOXA-23 carbapenemase gene of Acinetobacter baumannii // Emerg. Infect. Dis. 2010. Vol. 16, No. 1. P. 35–40.
78. Mussi M.A., Gaddy J.A., Cabruja M. [et al]. The opportunistic human pathogen Acinetobacter baumannii senses and responds to light // J. Bacteriol. 2010. Vol. 192, No. 24. P. 6336–6345.
79. Munier A., Biardb L., Legrandc M. [et al.]. Incidence, risk factors and outcome of multi-drug resistant Acinetobacter baumannii nosocomial infections during an outbreak in a burn unit // Int. J. Infect. Dis. 2019. Vol. 79. P. 179–184.
80. Nemec A., Krizova L., Maixnerova M. [et al]. Genotypic and phenotypic characterization of the Acinetobacter calcoaceticus – Acinetobacter baumannii complex with the proposal of Acinetobacter pittii sp. nov. (formerly Acinetobacter genomic species 3) and Acinetobacter nosocomialis sp. nov. (formerly Acinetobacter genomic species 13TU) // Res. Microbiol. 2011. Vol. 162, No. 4. P. 393–404.
81. Mussi M.A., Gaddy J.A., Cabruja M. [et al]. The opportunistic human pathogen Acinetobacter baumannii senses and responds to light // J. Bacteriol. 2010. Vol. 192, No. 24. P. 6336–6345.
82. Nishio H., Komatsu M., Shibata N. [et al.]. Metallo-β-lactamaseproducing gram-negative bacilli: Laboratory-based surveillance in cooperation with 13 clinical laboratories in the Kinki region of Japan // J. Clinic. Microbiol. 2004. Vol. 42, No. 11. P. 5256–5263.
83. Nemec A., Krizova L., Maixnerova M. [et al]. Genotypic and phenotypic characterization of the Acinetobacter calcoaceticus – Acinetobacter baumannii complex with the proposal of Acinetobacter pittii sp. nov. (formerly Acinetobacter genomic species 3) and Acinetobacter nosocomialis sp. nov. (formerly Acinetobacter genomic species 13TU) // Res. Microbiol. 2011. Vol. 162, No. 4. P. 393–404.
84. Seward R.J. Detection of integrons in worldwide nosocomial isolates of Acinetobacter spp. // Clin. Microbiol. Infect. 1999. Vol. 5, No. 6. P. 308–318.
85. Nishio H., Komatsu M., Shibata N. [et al.]. Metallo-β-lactamaseproducing gram-negative bacilli: Laboratory-based surveillance in cooperation with 13 clinical laboratories in the Kinki region of Japan // J. Clinic. Microbiol. 2004. Vol. 42, No. 11. P. 5256–5263.
86. Shaykh Baygloo N., Bouzari M., Rahimi F. [et al.]. Identification of genomic species of Acinetobacter isolated from burns of ICU patients // Arch. Iran Med. 2015. Vol. 18, No. 10. P. 638–642.
87. Seward R.J. Detection of integrons in worldwide nosocomial isolates of Acinetobacter spp. // Clin. Microbiol. Infect. 1999. Vol. 5, No. 6. P. 308–318.
88. Tekin R., Dal T., Bozkurt F. [et al]. Risk factors for nosocomial burn wound infection caused by multidrug resistant Acinetobacter baumannii // J. Burn. Care Res. 2014. Vol. 35, No. 1. P. 73–80.
89. Shaykh Baygloo N., Bouzari M., Rahimi F. [et al.]. Identification of genomic species of Acinetobacter isolated from burns of ICU patients // Arch. Iran Med. 2015. Vol. 18, No. 10. P. 638–642.
90. Tomaras A., Dorsey C., Edelmann R. [et al.]. Attachment to and biofilm formation on abiotic surfaces by Acinetobacter baumannii: Involvement of a novel chaperone-usher pili assembly system // Microbiology. 2003. Vol. 149. P. 3473–3484.
91. Tekin R., Dal T., Bozkurt F. [et al]. Risk factors for nosocomial burn wound infection caused by multidrug resistant Acinetobacter baumannii // J. Burn. Care Res. 2014. Vol. 35, No. 1. P. 73–80.
92. Van Looveren M., Goosens H. Antimicrobial resistance of Acinetobacter spp. in Europe // Clin. Microbiol. Infect. 2004. Vol. 10. P. 684–704.
93. Tomaras A., Dorsey C., Edelmann R. [et al.]. Attachment to and biofilm formation on abiotic surfaces by Acinetobacter baumannii: Involvement of a novel chaperone-usher pili assembly system // Microbiology. 2003. Vol. 149. P. 3473–3484.
94. Van Looveren M., Goosens H. Antimicrobial resistance of Acinetobacter spp. in Europe // Clin. Microbiol. Infect. 2004. Vol. 10. P. 684–704.
Review
For citations:
Fomicheva T.D., Skurikhina Yu.E., Sotnichenko S.A., Griban P.A., Fedorets V.V., Tymoshenko M.V., Ayvazian R.R. THE ROLE OF ACINETOBACTER BAUMANNII STRAINS IN THE DEVELOPMENT OF SEPTIC COMPLICATIONS IN CASE OF BURN INJURY. Pacific Medical Journal. 2019;(3):18-23. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2019.3.18-23
Views:
729
Email this article 