DEFEAT OF THE GASTROINTESTINAL TRACT IN HIV INFECTION
https://doi.org/10.17238/PmJ1609-1175.2019.3.24-28
Abstract
Morphological and functional disorders of digestive system in HIV-infection are found throughout the entire gastrointestinal tract: in oral cavity, esophagus, stomach, small and large intestine, liver, pancreas gland, gallbladder. A literature review on etiology and clinical manifestations of gastrointestinal tract in HIV-infected patients is presented. It is shown that digestive system affection in HIV-infection is caused not only by direct virus action but also by influence of opportunistic agents, and by chronic inflammation and immunodeficiency aggravation without antiretroviral therapy. Against the background of a specific treatment, gastrointestinal damage can develop due to polypharmacy. The use of probiotics may be considered a promising trend of intestine biocoenosis recovery in patients with HIVinfection.
About the Authors
G. M. Khasanova
Bashkirskyi State Medical University
Russian Federation
Russian Federation
3 Lenina St. Ufa 450008 Russian Federation
D. M. Urunova
Central Asian Center for Treatment, Care and
Support of PLHIV,
Institute of Advanced Training of Doctors
Uzbekistan
Uzbekistan
6–36 Chilonzar St. Tashkent 100097 Uzbekistan
51 Parkentskaya St. Tashkent 100007 Uzbekistan
Z. I. Akhmedzhanova
Central Asian Center for Treatment, Care and
Support of PLHIV,
Institute of Advanced Training of Doctors
Uzbekistan
Uzbekistan
6–36 Chilonzar St. Tashkent 100097 Uzbekistan
51 Parkentskaya St. Tashkent 100007 Uzbekistan
G. M. Giyasova
Central Asian Center for Treatment, Care and
Support of PLHIV,
Institute of Immunology and Human
Genomics
Uzbekistan
Uzbekistan
6–36 Chilonzar St. Tashkent 100097 Uzbekistan
74 Yahye Gulyamova St. Mirabad district, Tashkent 100060 Uzbekistan
A. A. Chernikova
Clinical Hospital № 2
Russian Federation
50 Borisenko St. Vladivostok 690001 Russian Federation
Russian Federation
50 Borisenko St. Vladivostok 690001 Russian Federation
A. N. Khasanova
Bashkirskyi State Medical University
Russian Federation
Russian Federation
3 Lenina St. Ufa 450008 Russian Federation
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Review
For citations:
Khasanova G.M., Urunova D.M., Akhmedzhanova Z.I., Giyasova G.M., Chernikova A.A., Khasanova A.N. DEFEAT OF THE GASTROINTESTINAL TRACT IN HIV INFECTION. Pacific Medical Journal. 2019;(3):24-28. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2019.3.24-28
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