PRIMARY MALIGNANT NEOPLASMS OF CEREBROSPINAL NERVOUS SYSTEM IN CHILDREN: PERSPECTIVES OF IMPROVEMENT OF DIAGNOSTIC AND TREATMENT APPROACHES
https://doi.org/10.17238/PmJ1609-1175.2019.2.8-10
Abstract
The article presents review of publications of cerebrospinal nervous system (CNS) tumors in children, their diagnostics, classification and therapy. Malignant neoplasms of CNS in children of different age are represented by a wide range of histomolecular groups. In the classification invented by WHO in 2016, for the first time, the basis for their separation was laid not only the histological structure, but also the most significant molecular genetic features or chromosomal aberrations. These features broaden the possibilities of target therapy, enable to minimize toxic effects and correct timing as well as to improve programmed treatment and to increase survival index.
About the Authors
A. R. Volkova
Kazan State Medical University
Russian Federation
49 Butlorov St. Kazan 420012 Russian Federation
Russian Federation
49 Butlorov St. Kazan 420012 Russian Federation
Kh. M. Vahitov
Kazan State Medical University
Russian Federation
49 Butlorov St. Kazan 420012 Russian Federation
Russian Federation
49 Butlorov St. Kazan 420012 Russian Federation
E. V. Kumirova
Pirogov Russian National Research Medical
University,
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
Russian Federation
1 Ostrovitianov St. Moscow 117997 Russian Federation
1 SamoryMashela St. Moscow 117997 Russian Federation
R. Z. Shammasov
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
Russian Federation
1 SamoryMashela St. Moscow 117997 Russian Federation
Russian Federation
1 SamoryMashela St. Moscow 117997 Russian Federation
E. I. Nizamutdinova
Republican Childrens Clinical Hospital Ministry of Health of Tatarstan
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
I. V. Osipova
Republican Childrens Clinical Hospital Ministry of Health of Tatarstan
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
E. N. Grishina
Republican Childrens Clinical Hospital Ministry of Health of Tatarstan
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
L. P. Karimova
Republican Childrens Clinical Hospital Ministry of Health of Tatarstan
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
Russian Federation
140 Orenbursky Path, Kazan 420059 Russian Federation
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Review
For citations:
Volkova A.R., Vahitov Kh.M., Kumirova E.V., Shammasov R.Z., Nizamutdinova E.I., Osipova I.V., Grishina E.N., Karimova L.P. PRIMARY MALIGNANT NEOPLASMS OF CEREBROSPINAL NERVOUS SYSTEM IN CHILDREN: PERSPECTIVES OF IMPROVEMENT OF DIAGNOSTIC AND TREATMENT APPROACHES. Pacific Medical Journal. 2019;(2):8-10. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2019.2.8-10
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