THE CHOROIDAL BLOOD FLOW OF EYE DURING PREGNANCY AND IN POSTNATAL PERIOD IN WOMEN WITH PREECLAMPSIA, CLINICAL PART FOR PREDICTING RISK OF VASCULAR PATHOLOGY OF POSTERIOR SEGMENT OF THE EYE
https://doi.org/10.17238/PmJ1609-1175.2019.2.43-46
Abstract
Objective: to determine risk factors of vascular pathology of posterior segment of the eye in pregnant women with preeclampsia (PE).
Methods: The main group: 42 pregnant women with PE. The 1st experimental group: 30 women with physiological gestation course. The 2nd experimental group: 27 non-pregnant women with vascular pathology of posterior segment of the eye. The control group: 25 healthy non-pregnant women. We determined linear blood flow rate in short posterior ciliary arteries and prothrombin ratio.
Results: In group of pregnant women with PE in the III trimester we registered a decrease of average values of linear blood flow rate which in most cases increased to normal values by 6-8th months of after delivery period. These values remained decreased in 12 women that matched with the growth of prothrombin ratio. Occlusions of retinal veins has formed in mentioned cases 1.5–3.5 years later.
Conclusions: Studies of linear blood flow rate in short posterior ciliary arteries and level of prothrombin ratio in pregnancy complicated by PE can detect a group of women with increased risk factor of formation of vascular pathology of posterior segment of the eye during a year after delivery.
About the Authors
E. L. Sorokin
Khabarovsk branch of S.N. Fyodorov NMRC “MNTK “Eye Microsurgery”
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
O. V. Kolenko
Khabarovsk branch of S.N. Fyodorov NMRC “MNTK “Eye Microsurgery”,
Postgraduate Institute for Public Health Workers
Russian Federation
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
9 Krasnodarskaya St. Khabarovsk 680000 Russian Federation
N. S. Khodzhaev
S.N. Fyodorov NMRC “MNTK “Eye Microsurgery”
Russian Federation
59a Beskudnikovskii blvd. Moscow 127486 Russian Federation
Russian Federation
59a Beskudnikovskii blvd. Moscow 127486 Russian Federation
N. V. Pomytkina
Khabarovsk branch of S.N. Fyodorov NMRC “MNTK “Eye Microsurgery”
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
G. V. Chizhova
Postgraduate Institute for Public Health Workers
Russian Federation
9 Krasnodarskaya St. Khabarovsk 680000 Russian Federation
Russian Federation
9 Krasnodarskaya St. Khabarovsk 680000 Russian Federation
Yu. N. Berdakov
Perinatal Center
Russian Federation
85 Istomina St. Khabarovsk 680028 Russian Federation
Russian Federation
85 Istomina St. Khabarovsk 680028 Russian Federation
A. A. Fil
Khabarovsk branch of S.N. Fyodorov NMRC “MNTK “Eye Microsurgery”
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
Ya. E. Pashentsev
Khabarovsk branch of S.N. Fyodorov NMRC “MNTK “Eye Microsurgery”
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
Russian Federation
211 Tikhookeanskaya St. Khabarovsk 680033 Russian Federation
References
1. Pomytkina N.V., Sorokin Е.L., Egorov V.V., Pashencev Ya.E. Creation of algorithm for retinal vein thrombosis prediction in patients with hypertensive disease and evaluation of its effectiveness // Information Science and Control Systems. 2016. No. 3. P. 55–61.
2. Kolenko О.V., Sorokin Е.L., Egorov V.V. Studying of patterns of dynamics of macular retina micromorphometric indicators in pregnant women at pathological pregnancy in interrelation with gestosis severity // Kuban Scientific Medical Bulletin. 2013. No. 2. P. 48–52.
3. Bondar T.P., Syanova Yu.А., Bayramkulova А.I., Syanov А.Yu. Indicators of the internal and external pathways of hemocoagulation in acute cerebral circulatory disorders of ischemic or hemorrhagic type in conditions of thrombocytopenia // Modern Science and Innovation. 2016. Vol. 2, No. 14. P. 157–167.
4. Kolenko О.V., Sorokin Е.L., Bloshchinskaya I.А. [et al.]. Condition of macular retina in women at preeclampsia and after the delivery // Journal of Ophthalmology. 2015. No. 3. P. 47–53.
5. Kiseleva Т.N., Koshevaya О.P., Budzinskaya I.V. [et al.]. Value of color Doppler imaging in the diagnosis of occlusive retinal venous lesions // The Russian Annals of Ophthalmology. 2006. No. 5. P. 4–7.
6. Rykun V.S., Peyutina N.V. Retinal veins thrombosis and limited blood supply of choroid – are they interrelated? // Modern Problems of Science and Education. 2011. No. 6. С. 1–5.
7. Kolenko О.V., Sorokin Е.L., Egorov V.V. Micromorphometric indicators of the macular retina in women with a pathological pregnancy // Modern Technologies in Ophthalmology. 2014. No. 2. P. 76–78.
8. Kolenko О.V., Sorokin Е.L., Egorov V.V. Studying of patterns of dynamics of macular retina micromorphometric indicators in pregnant women at pathological pregnancy in interrelation with gestosis severity // Kuban Scientific Medical Bulletin. 2013. No. 2. P. 48–52.
9. Sukhikh G.Т., Vikhlyaev Е.М., Vanko L.V. [et al.]. Endothelial dysfunction in the genesis of perinatal pathology // Obstetrics and Gynecology. 2008. No. 5. С. 3–7.
10. Kolenko О.V., Sorokin Е.L., Egorov V.V. Method of prediction of vascular pathology of sight organ at women after pregnancy complicated with gestosis: Patent for Invention RUS 2350962 15.11.2007.
11. Tikhomirova А.А., Zolotareva А.S. Changes in coagulogram indices of patients diagnosed with hemorrhagic stroke, arterial hypertension // Newsletter of Modern Research. 2018. No. 5.3. P. 76–83.
12. Kolenko О.V., Sorokin Е.L., Bloshchinskaya I.А. [et al.]. Condition of macular retina in women at preeclampsia and after the delivery // Journal of Ophthalmology. 2015. No. 3. P. 47–53.
13. Kolenko О.V., Sorokin Е.L., Bloshchinskaya I.А. [et al.]. Patterns of morphometric parameters of the macula in preeclampsia and their clinical significance // Pacific Medical Journal. 2018. No. 2. P. 59–62.
14. Kolenko О.V., Sorokin Е.L., Egorov V.V. Micromorphometric indicators of the macular retina in women with a pathological pregnancy // Modern Technologies in Ophthalmology. 2014. No. 2. P. 76–78.
15. Goebel W., Lieb W.E., Ho A. [et al.]. Color Doppler imaging: A new technique to assess orbital blood flow in patients with diabetic retinopathy // Investigative Ophthalmology & Visual Science. 1995. Vol. 36, No. 5. P. 864–870.
16. Kolenko O.V., Pomytkina N.V., Sorokin Е.L., Pashencev Ya.Е. Morphometric studies of the macular retina in pregnancy complicated by preeclampsia // The Scientific and Practical Medical Journal. 2018. No. 3. P. 97–100.
17. Kolenko О.V., Sorokin Е.L., Egorov V.V. Method of prediction of vascular pathology of sight organ at women after pregnancy complicated with gestosis: Patent for Invention RUS 2350962 15.11.2007.
18. Linsenmeier R.A., Padnick-Silver L. Metabolic dependence of photoreceptors on the choroid in the normal and detached retina // Investigative Ophthalmology & Visual Science. 2000. Vol. 41, No. 10. P. 3117–3123.
19. Pomytkina N.V., Sorokin Е.L. Development of prognostic algorithm of identification of retinal vein occlusions risk in patients with hypertonic disease during the periods of geomagnetic disturbances // The Scientific and Practical Medical Journal. 2012. No. 4–2. P. 136–139.
20. Kolenko О.V., Sorokin Е.L., Bloshchinskaya I.А. [et al.]. Patterns of morphometric parameters of the macula in preeclampsia and their clinical significance // Pacific Medical Journal. 2018. No. 2. P. 59–62.
21. Pomytkina N.V., Sorokin Е.L., Egorov V.V., Pashencev Ya.E. Creation of algorithm for retinal vein thrombosis prediction in patients with hypertensive disease and evaluation of its effectiveness // Information Science and Control Systems. 2016. No. 3. P. 55–61.
22. Kolenko O.V., Pomytkina N.V., Sorokin Е.L., Pashencev Ya.Е. Morphometric studies of the macular retina in pregnancy complicated by preeclampsia // The Scientific and Practical Medical Journal. 2018. No. 3. P. 97–100.
23. Rykun V.S., Peyutina N.V. Retinal veins thrombosis and limited blood supply of choroid – are they interrelated? // Modern Problems of Science and Education. 2011. No. 6. С. 1–5.
24. Pomytkina N.V., Sorokin Е.L. Development of prognostic algorithm of identification of retinal vein occlusions risk in patients with hypertonic disease during the periods of geomagnetic disturbances // The Scientific and Practical Medical Journal. 2012. No. 4–2. P. 136–139.
25. Sukhikh G.Т., Vikhlyaev Е.М., Vanko L.V. [et al.]. Endothelial dysfunction in the genesis of perinatal pathology // Obstetrics and Gynecology. 2008. No. 5. С. 3–7.
26. Pomytkina N.V., Sorokin Е.L., Egorov V.V., Pashencev Ya.E. Creation of algorithm for retinal vein thrombosis prediction in patients with hypertensive disease and evaluation of its effectiveness // Information Science and Control Systems. 2016. No. 3. P. 55–61.
27. Tikhomirova А.А., Zolotareva А.S. Changes in coagulogram indices of patients diagnosed with hemorrhagic stroke, arterial hypertension // Newsletter of Modern Research. 2018. No. 5.3. P. 76–83.
28. Rykun V.S., Peyutina N.V. Retinal veins thrombosis and limited blood supply of choroid – are they interrelated? // Modern Problems of Science and Education. 2011. No. 6. С. 1–5.
29. Goebel W., Lieb W.E., Ho A. [et al.]. Color Doppler imaging: A new technique to assess orbital blood flow in patients with diabetic retinopathy // Investigative Ophthalmology & Visual Science. 1995. Vol. 36, No. 5. P. 864–870.
30. Sukhikh G.Т., Vikhlyaev Е.М., Vanko L.V. [et al.]. Endothelial dysfunction in the genesis of perinatal pathology // Obstetrics and Gynecology. 2008. No. 5. С. 3–7.
31. Linsenmeier R.A., Padnick-Silver L. Metabolic dependence of photoreceptors on the choroid in the normal and detached retina // Investigative Ophthalmology & Visual Science. 2000. Vol. 41, No. 10. P. 3117–3123.
32. Tikhomirova А.А., Zolotareva А.S. Changes in coagulogram indices of patients diagnosed with hemorrhagic stroke, arterial hypertension // Newsletter of Modern Research. 2018. No. 5.3. P. 76–83.
33. Goebel W., Lieb W.E., Ho A. [et al.]. Color Doppler imaging: A new technique to assess orbital blood flow in patients with diabetic retinopathy // Investigative Ophthalmology & Visual Science. 1995. Vol. 36, No. 5. P. 864–870.
34. Linsenmeier R.A., Padnick-Silver L. Metabolic dependence of photoreceptors on the choroid in the normal and detached retina // Investigative Ophthalmology & Visual Science. 2000. Vol. 41, No. 10. P. 3117–3123.
Review
For citations:
Sorokin E.L., Kolenko O.V., Khodzhaev N.S., Pomytkina N.V., Chizhova G.V., Berdakov Yu.N., Fil A.A., Pashentsev Ya.E. THE CHOROIDAL BLOOD FLOW OF EYE DURING PREGNANCY AND IN POSTNATAL PERIOD IN WOMEN WITH PREECLAMPSIA, CLINICAL PART FOR PREDICTING RISK OF VASCULAR PATHOLOGY OF POSTERIOR SEGMENT OF THE EYE. Pacific Medical Journal. 2019;(2):43-46. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2019.2.43-46
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