RESULTS OF OPTIC NERVE ELECTROSTIMULATION IN COMBINATION WITH THE USE OF PEPTIDE REGULATOR IN PATIENTS WITH GLAUCOMA
https://doi.org/10.17238/PmJ1609-1175.2019.2.88-91
Abstract
Objective: is to assess the effectiveness of complex treatment of stabilized primary open-angle incipient glaucoma with normal intraocular pressure including parabulbar administration of ‘Cortexin’ and electrostimulation of optic nerve.
Methods: We examined 42 patients (72 eyes) with stabilized primary open-angle incipient glaucoma. 32 patients (56 eyes) were administered 10 mg of “Cortexin” parabulbarly and retina and optic nerve were (1st group), 10 patients (16 eyes) received only hypotensive therapy (2nd group, control).
Results: Electrostimulation in combination with neuroprotective therapy enabled to improve vision acuity in 83 %, peripheral visual field by 50° in average (eight meridians in total) – in 91 % of patients. In 94 % of cases in average electrosensitivity of visual system decreased by120.8 μA, and electrolability increased by 5.2 Hz.
Conclusions: The proposed method of complex treatment of glaucoma improves the stability of the nerve cells of the eye to pathological factors causing a decrease in visual functions, and can be considered an effective method aimed at their preservation and stabilization of the glaucomatous process.
About the Authors
E. V. SorokinaRussian Federation
32 Bolnichnaya St. Blagoveshchensk 675000 Russian Federation
V. N. Krasnogorskaya
Russian Federation
32 Bolnichnaya St. Blagoveshchensk 675000 Russian Federation
95 Gorkogo St. Blagoveshchensk 675000 Russian Federation
A. A. Petrova
Russian Federation
82 Kalinina St. Blagoveshchensk 675000 Russian Federation
A. Y. Bekker
Russian Federation
95 Gorkogo St. Blagoveshchensk 675000 Russian Federation
References
1. Erichev V.P., Shamshinova A.M., Lovpache D.N. Comparative evaluation of the neuroprotective effect of peptide bioregulators in patients with different stages of primary open-angle glaucoma // Glaucoma. 2005. No. 1. P. 18–24.
2. Liebman E.S., Shakhova E.V., Chumayeva E.A. [et al.]. Idlidity due to glaucoma in Russia // Glaucoma: problems and solutions: Sat. scientific. articles. Moscow, 2004. P. 430–432.
3. Marchenko L.N. Neuroprotection in diseases of the retina and optic nerve. Minsk, 2003. 363 p.
4. National guide for glaucoma for polyclinic doctors / ed. by E.A. Egorov, Yu.S. Astakhov, A.G. Shchuko. Moscow: Stolichniy Business, 2008. 136 p.
5. Nesterov A.P. Primary open-angle glaucoma: Pathogenesis and principles of treatment // Clinical ophthalmology. 2000. Vol. 1, No. 1. P. 4–5
6. Safina Z.M. Electrostimulation in the clinic of eye diseases: Methodical recommendations for ophthalmologists. Ufa, 2000. 18 p.
7. Physiotherapeutic methods of treatment of glaucoma: Tutorial / Egorov V.V., Smolyakova T.V., Borisova T.V. [et al.]. Khabarovsk, 2006. 114 p.
Review
For citations:
Sorokina E.V., Krasnogorskaya V.N., Petrova A.A., Bekker A.Y. RESULTS OF OPTIC NERVE ELECTROSTIMULATION IN COMBINATION WITH THE USE OF PEPTIDE REGULATOR IN PATIENTS WITH GLAUCOMA. Pacific Medical Journal. 2019;(2):88-91. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2019.2.88-91