Differentiated approaches to the treatment of urinary tract infection in children taking into account the etiological factor Enterococcus faecalis
E. A. Melnikova,
E. A. Zaitseva,
V. N. Luchaninova,
E. V. Krukovich,
T. S. Komenkova,
Yu. V. Feoktistova https://doi.org/10.34215/1609-1175-2019-4-60-65
Abstract
Objective: The objective is to develop an algorithm of initial antimicrobial treatment of urinary tract infection (UTI) concidering the etiological factor Enterococcus faecalis, having spontaneous resistance to cephalosporins.
Methods: The analysis of 6438 results of urine bacteriological examination of children with UTI, having received the treatment in multi-field children’s hospital for 9 years, and clinical manifestations of UTI associated with E. faecalis in 181 patients was carried out. Addirionally, antimicrobial susceptibility testing was carried out in 60 cultures of E. faecalis.
Results: E. faecalis is occurred to be the second etiological factor of UTI in order of importance in children and had high priority in its development in newborns. The detected diagnostic markers of UTI associated with E. faecalis, and its antimicrobial susceptibility are represented in the author-developed algorithm of the initial antimicrobial treatment.
Conclusions: The algorithm of the initial antimicrobial treatment of UTI caused by E. faecalis will help to prescribe a sustainable, early antimicrobial treatment at the stage of microbe identification.
About the Authors
E. A. Melnikova
Regional Children's Clinical Hospital No. 1;
Pacific State Medical University
Russian Federation
Russian Federation
Elena A. Melnikova, MD, head of the Regional Children’s Uronephrology Center, Children’s Clinical Hospital No. 1; assistant of Pediatrics Institute, Pacific State Medical University
27 Ostryakova Ave., Vladivostok, 690078,2
Ostryakova Ave., Vladivostok, 690002
E. A. Zaitseva
Pacific State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
V. N. Luchaninova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Saint Petersburg
Russian Federation
Saint Petersburg
E. V. Krukovich
Pacific State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
T. S. Komenkova
Pacific State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
Yu. V. Feoktistova
Regional Children's Clinical Hospital No. 1;
Pacific State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
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Review
For citations:
Melnikova E.A., Zaitseva E.A., Luchaninova V.N., Krukovich E.V., Komenkova T.S., Feoktistova Yu.V. Differentiated approaches to the treatment of urinary tract infection in children taking into account the etiological factor Enterococcus faecalis. Pacific Medical Journal. 2019;(4):60-65. (In Russ.) https://doi.org/10.34215/1609-1175-2019-4-60-65
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