Clinical features of infectious mononucleosis in children, depending on the etiological factor
https://doi.org/10.34215/1609-1175-2019-4-70-73
Abstract
Objective: The objective is to analyze clinical and laboratory features of infectious mononucleosis (IM) depending on disease etiology.
Methods: 102 children with IM aged from 1 to 15 y.o. were examined. Polymerase chain reaction and immunoenzyme method were used to verify disease etiology.
Results: In patients with Epstein–Barr virus and mixed infection, the most pronounced manifestations of lymphoproliferative syndrome and tonsillitis, high content of atypical mononuclear cells in peripheral blood are detected. Aspects of IM of cytomegaloviral etiology were notable for the prevalence of toxic syndrome along with other less pronounced clinical and laboratory manifestations of the disease.
Conclusions: The detected features of the aspects of IM depending on etiological factor allow to prognosticate a variant and a character of the disease course and to early improve the therapy.
About the Authors
G. P. Martynova
Krasnoyarsk State Medical University named after professor V.F. Voino-Yasenetsky
Russian Federation
Russian Federation
Galina P. Martynova, MD, PhD, professor, head of the Department of Children’s Infectious Diseases
1 Partizana Zheleznyaka St., Krasnoyarsk, 660022
L. A. Ikkes
Krasnoyarsk State Medical University named after professor V.F. Voino-Yasenetsky
Russian Federation
Krasnoyarsk
Russian Federation
Krasnoyarsk
Ya. A. Bogvilenе
Krasnoyarsk State Medical University named after professor V.F. Voino-Yasenetsky
Russian Federation
Krasnoyarsk
Russian Federation
Krasnoyarsk
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Review
For citations:
Martynova G.P., Ikkes L.A., Bogvilenе Ya.A. Clinical features of infectious mononucleosis in children, depending on the etiological factor. Pacific Medical Journal. 2019;(4):70-73. (In Russ.) https://doi.org/10.34215/1609-1175-2019-4-70-73
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