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Comatotropny hormone and insulin-like growth factors in the pathogenesis of fetal growth retardation

Abstract

Review article on the endocrine regulation of fetal growth retardation. Somatomedins and growth hormone have a similar structure of the peptide, but their influence on fetal growth varies. During pregnancy, the insulin growth factor-2 plays an important role, after the birth-insulin-like growth factor-1. Hormonal profile of the mother, her somatic disorders, the impact of external factors, production of hormones by the placenta, and gene polymorphism insulin-like growth factors influence the development of the fetus and newborn.

About the Authors

V. V. Kocherova
Chita State Medical Academy
Russian Federation


V. A. Scherbak
Chita State Medical Academy
Russian Federation


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Kocherova V.V., Scherbak V.A. Comatotropny hormone and insulin-like growth factors in the pathogenesis of fetal growth retardation. Pacific Medical Journal. 2016;(1):5-8. (In Russ.)

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ISSN 1609-1175 (Print)