Age-related features of the organization of the microcirculatory bed of the bulbar conjunctiva
https://doi.org/10.34215/1609-1175-2020-3-57-61
Abstract
Objective: Analysis of age-related changes of microcirculatory bed of bulbar conjunctiva.
Methods: 46 individuals of both sexes, divided into 5 age groups according to WHO recommendations, were examined. Biomicroscopy of bulbar conjunctiva was performed using a non-mydriatic retinal camera TOPCON TRC-NW8F (Japan); the obtained images were processed with a mea‑ suring device of automated analysis system ImageScope (Leica, Germany).
Results: The average diameter of arterioles, arterioleto-venule ratio (AVR) and specific density of capillaries were the largest, and the diameter of venules was the smallest among the subjects aged 18–44 years. The most sensitive indicators of the state of microcirculatory bed were AVR and the specific density of capillaries, the values of which in the group of 45–59-year-olds were 10–11% lower than in people aged 18–24 and 25–44 years. Differences in other indicators between people aged 18-24 and 45–59 years were not significant. Between the groups of 60–74 and 75–86-year-old participants of the study, pronounced differences (about 18%) were found only in the specific density of capillaries: compared with 18–24 and 45–59-year-olds, this indicator decreased by almost 1.5 times, AVR – only by a third, and changes in the average diameter of arterioles and venules did not exceed 9–12%. Elderly people more often demonstrated arteriolar spasm, their uneven caliber, avascular fields and other disorders of the structure of the micro‑ circulatory bed.
Conclusions: As the body ages, in the microcirculatory bed of the bulbar conjunctiva, the number of atypical vascular formations increases, the diameter of the arterioles decreases, the AVR and the specific density of capillaries decrease, the diameter of the venules increases.
About the Authors
V. M. Chertok
Pacific State Medical University
Russian Federation
Russian Federation
MD, PhD, professor, head of the Department of Human Anatomy,
2, Ostryakova Ave., Vladivostok, 690002
V. A. Nevzorova
Pacific State Medical University
Russian Federation
Russian Federation
MD, PhD, professor, head of the Institute of Intrinic Medicine and Instrumental diagnostics,
2, Ostryakova Ave., Vladivostok, 690002
A. K. Savchenko
Pacific State Medical University
Russian Federation
Russian Federation
student,
2, Ostryakova Ave., Vladivostok, 690002
O. V. Miroshnichenko
Medical Center, Far Eastern Federal University
Russian Federation
Russian Federation
MD, PhD,
10 Ajax Bay, Russky Island, Vladivostok, 690922
A. V. Laryushkina
Pacific State Medical University
Russian Federation
Russian Federation
MD, PhD, associate professor,
2, Ostryakova Ave., Vladivostok, 690002
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Review
For citations:
Chertok V.M., Nevzorova V.A., Savchenko A.K., Miroshnichenko O.V., Laryushkina A.V. Age-related features of the organization of the microcirculatory bed of the bulbar conjunctiva. Pacific Medical Journal. 2020;(3):57-61. (In Russ.) https://doi.org/10.34215/1609-1175-2020-3-57-61
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