DEVELOPMENT OF TECHNOLOGY FOR QUICK-DISSOLVING FORM OF SODIUM ALGINATE
Abstract
Brown algae polysaccharides - are the alginates widely used in food and pharmaceutical industries as health promoting medicines in case of poisoning with heavy metals salts and radionuclides. A significant shortcoming of the alginates is their poor solubility. The purpose of research is development of a method enhancing the sodium alginate solubility based on a transferring the part of uronic acids residues in the alginate molecule to the calcium salts form. Methods. The article covers the influence of calcium content on the alginate solubility. The researchers formed sorption isotherm of calcium ions by sodium alginate in the environment of 50 % ethanol and obtained the alginate samples containing from 0.2 to 6.82 % of calcium. Also they studied the hydrogels properties of the obtained samples of calcium alginate. Results. It was found that in the case of calcium content in the alginate less than 4.44 % a partial dissolution of the alginate gel starts, while calcium content less than 0.8 % promotes a complete dissolution. There have been also an estimation of dissolution rate for various alginate samples. Calcium alginate samples containing 0.2-0.8 % of calcium showed a higher rate of dissolution by 6.2-13.4 times than the original sodium alginate. Conclusions. Technology for producing incomplete calcium salts of alginates may be a new and very efficient approach to the problem of their solubility and, therefore, improvement of consumer properties.
About the Authors
V. V. Kovalev
Institute of Marine Biology named after A.V. Zhirmunskiy FEB RAS; Far Eastern Federal University
Russian Federation
Russian Federation
R. Yu. Khotimchenko
Institute of Marine Biology named after A.V. Zhirmunskiy FEB RAS; Far Eastern Federal University
Russian Federation
Russian Federation
E. A. Podkorytova
Institute of Marine Biology named after A.V. Zhirmunskiy FEB RAS
Russian Federation
Russian Federation
E. V. Khozhaenko
Institute of Marine Biology named after A.V. Zhirmunskiy FEB RAS; Far Eastern Federal University
Russian Federation
Russian Federation
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Review
For citations:
Kovalev V.V., Khotimchenko R.Yu., Podkorytova E.A., Khozhaenko E.V. DEVELOPMENT OF TECHNOLOGY FOR QUICK-DISSOLVING FORM OF SODIUM ALGINATE. Pacific Medical Journal. 2014;(2):88-92. (In Russ.)
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