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Тихоокеанский медицинский журнал

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Нейрогистохимические исследования ферментов в судебной медицине

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Аннотация

Приводятся основные положения фундаментальных нейрогистохимических исследований, выполненных П.А. Мотавкиным и его учениками, посвященных изучению ферментов и дифференцированной медиаторной организации головного мозга. Результаты научно-исследовательских работ, проведенных в последние годы, успешно внедрены в практику судебно-медицинской танатологии и токсикологии. Показаны перспективы развития данного научного направления.

Об авторах

Ю. И. Пиголкин
Первый Московский государственный медицинский университет им. И.М. Сеченова
Россия


Ю. Е. Морозов
Балтийский федеральный университет им. И. Канта
Россия


Список литературы

1. Zimatkin S.M. The aldehyde brain and their role in the pathogenesis of alcoholism Grodno: GrGMU, 2008. 308 p.

2. Zimatkin S.M. The histaminergic system of brain. Grodno: GrGMU, 2007. 262 p.

3. Zimatkin S.M. The alcohol oxidation in the brain. Grodno: GrGMU, 2006. 200 p.

4. Konovko O.O., Djujzen I.V., Motavkin P.A. Ethanol oxidized and NO-synthesized enzymes monoaminergic nuclei of the human brain, Bjul. jeksperim. biol. i med. 2003. Vol. 136, No. 8. T. 231-234.

5. Konovko O.O., Morozov Ju.E., Kalinichenko S.G. et al. The induction of NO-synthase and acetaldehyde dehydrogenase in the neurons of the human cerebellar cortex under chronic alcohol intoxication, Bjul. jeksperim. biol. i med. 2004. Vol. 137, No. 2. P. 237-240.

6. Mamedov V.K., Morozov Ju.E., Pigolkina E.Ju. The tolerance to ethanol and severity assessment of acute alcohol intoxication, Azerbaycan Metabolism jurnali. 2002. No. 2. P 30-33.

7. Morozov Ju.E. The forensic value products of enzymatic oxidation of ethanol in the corpse brain, Sudebno-medicinskaja jekspertiza. 2002. Vol. 45, No. 1. P. 17-21.

8. Morozov Ju.E., Ohotin V.E., Kalinichenko S.G. The value of ethanol oxidizing enzymes of the brain to the forensic diagnosis of alcoholic cardiomyopathy, Problemy jekspertizy v medicine. 2001. Vol. 1, No. 4. P. 11-16.

9. Motavkin P.A., Djujzen I.V. The nitroxidergic mechanisms of pain, Pacific Medical Journal. 2003. No. 2. P 11-16.

10. Motavkin P.A. The nitric oxide in the organs of the digestive system, Pacific Medical Journal. 2004. No. 2. P 13-17.

11. Motavkin P.A. What and how is innervate in the brain, Morfologija. 2007. Vol. 131, No. 1. P. 82-84.

12. Motavkin P.A., Chertok V.M. The brain innervation, Pacific Medical Journal. 2008. No. 3. P11-23.

13. Pigolkin Ju.I., Bogomolov D.V., Dolzhanskij O.V., Bogomolova I.N. The morphological changes of the brain in opium addiction, Sovr. aspekty terapii i profilaktiki nervno-psihicheskih rasstrojstv: sb. mat. Mezhdunarodnoj nauch.-prakt. konf. Vladivostok, 2002. P. 135-137.

14. Pigolkin Ju.I., Morozov Ju.E. The alcohol oxidizing diaphorase and dynamics of ethanol content in acute alcohol intoxication, Morfologija. 2006. V. 129, No. 2. P. 76-77.

15. Pigolkin Ju.I., Morozov Ju.E., Bogomolov D.V. The adrenal pathology under cannabinoid and opioid addiction, Aktualnye aspekty sudebnoj mediciny. Vypusk VII / ed. V.I. Vitera. Izhevsk, 2001. P. 74-77.

16. Pigolkin Ju.I., Morozov Ju.E., Ohotin V.E. The brain alcohol dehydrogenase - a marker of individual tolerance for alcohol intoxication to ketanolu, Sudebno-medicinskaja jekspertiza. 2002. Vol. 45, No. 3. P. 5-9.

17. Pigolkin Ju.I., Morozov Ju.E., Salomatin E.M., Mamedov V.K. The forensic medical evaluation of comprehensive toxicological researches, Sudebno-medicinskaja jekspertnaja dejatel’nost: problemy i perspektivy: sb. nauch. rabot / ed. V.S. Melnikova. Kirov, 2002. P. 192-198.

18. Pigolkin Ju.I., Sosedko Ju.I., Bogomolov D.V., Romanenko G.H. Forensic analysis of substance abuse with fatalities, Sovremennye problemy nejrobiologii: tez. dokl. Mezhdunarodnogo simpoziuma. Saransk, 2001. P. 124-125.

19. Pigolkina E.Ju., Morozov Ju.E., Tarasov Ju.A. The acetaldehyde: neuromodulator of alcohol intoxication, Sudebno-medicinskaja jekspertiza. 2002. V. 45, No. 4. P. 40-46.

20. Tiwenko O.V., Eliseeva E.V, Motavkin P.A. The significance of nitric oxide in the development of cardiac hypertrophy under experimental renal hypertension, Citologija. 2002. V. 44, No. 3. P. 263-269.

21. Dyuizen I.V., Deridovich I.I., Kurbatskii R.A. et al. NO-ergic neurons of the cervical nucleus of the rat brain in normal conditions and after administration of opiates, Neuroscience and Behavioral Physiology. 2004. Vol. 34. P. 621-626.

22. Kalinichenko S., Dudina Y.I., Dyuizen I.V., Motavkin P.A. Induction of synthase and glial acidic fibrillary protein in astrocytes in the temporal cortex of the rat with audiogenic epileptiform reactions, Neuroscience and Behavioral Physiology. 2005. Vol. 35. No. 6. P. 629-634.

23. Motavkin P.A., Okhotin V.E., Konovko O.O., Zimatkin S.M. Localization of alcohol- and aldehydedehydrogenase in the human spinal cord and brain, Neuroscience and Behavioral Physiology. 1990. No. 2. C. 7984.

24. Nakanishi N., Nakamura K., Ichikawa S. et al. Relationship between lifestyle and serum lipid and lipoprotein levels in middle-aged Japanese men, Eur. J. Epidemiol. 1999. Vol. 4. P 34133448.

25. Sivukhina E.V., Poskrebysheva A.S., Morozov Y.E. et al. Altered hypothalamic-pituitary-adrenal axis activity in patients with chronic heart failure, Hormone and Metabolic Research. 2009. Vol. 41. P 778-784.

26. Sivukhina E.V, Dolzhikov A. A., Morozov Y.E. et al. Comparison of vasopressin and oxytocin expressions in the hypothalamo-neurohypophysial system of patients with chronic heart failure, Hormone and Metabolic Research. 2010. Vol. 42. P 56-60.

27. Zimatkin S.M., Buben A.L. Ethanol oxidation in the living brain, Alcohol and Alcoholism. 2007. Vol. 42. No. 6. P. 529-532.

28. Zimatkin S.M., Kuznetsova V.B., Strik O.N. Spatial organization and morphometric characteristics of histaminergic neurons in the rat brain, Neuroscience and Behavioral Physiology. 2006. Vol. 36, No. 5. P 467-471.

29. Zimatkin S.M., Pronko S.P, Vasiliou V et.al. Enzymatic mechanisms of ethanol oxidation in the brain, Alcoholism: Clinical and Experimental Research. 2006. Vol. 30, No. 9. P 1500-1505.


Для цитирования:


Пиголкин Ю.И., Морозов Ю.Е. Нейрогистохимические исследования ферментов в судебной медицине. Тихоокеанский медицинский журнал. 2012;(2):89-93.

For citation:


Pigolkin Yu.I., Morozov Yu.E. Neurohistochemical studies of enzymes in forensic medicine. Pacific Medical Journal. 2012;(2):89-93. (In Russ.)

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