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Trospium Chloride in combination therapy of female genital prolapses and overactive bladder syndrome

Abstract

Based upon 28 follow-ups (women aged 55 to 82 years), the authors have researched into the efficiency of the trospium chloride used to treat overactive bladder syndrome followed by the surgical correction of genital prolapse. The results of urodynamic surveillance confirm this drug to be more efficient in cases of the detrusor hyperactivity. In cases of the overactive bladder syndrome with no detrusor hyperactivity the efficacy of the trospium chloride appears to be less obvious. The authors point to low occurrence and intensity of drug side effects. This allows to conclude that applying the trospium chloride is allowed from the patients’ safety standpoint to treat patients with the overactive bladder syndrome remained after surgical correction of genital prolapses.

About the Authors

M. E. Shkolnikov
Russian State Medical University named after N.I. Pirogov
Russian Federation


E. B. Mazo
Russian State Medical University named after N.I. Pirogov
Russian Federation


G. G. Krivoborodov
Russian State Medical University named after N.I. Pirogov
Russian Federation


Yu. E. Dobrokhotova
Russian State Medical University named after N.I. Pirogov
Russian Federation


M. M. Kaifajan
Russian State Medical University named after N.I. Pirogov
Russian Federation


L. V. Fandeeva
Russian State Medical University named after N.I. Pirogov
Russian Federation


R. F. Nurullin
Russian State Medical University named after N.I. Pirogov
Russian Federation


M. S. Zhdanova
Russian State Medical University named after N.I. Pirogov
Russian Federation


References

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Review

For citations:


Shkolnikov M.E., Mazo E.B., Krivoborodov G.G., Dobrokhotova Yu.E., Kaifajan M.M., Fandeeva L.V., Nurullin R.F., Zhdanova M.S. Trospium Chloride in combination therapy of female genital prolapses and overactive bladder syndrome. Pacific Medical Journal. 2011;(1):26-28. (In Russ.)

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ISSN 1609-1175 (Print)