Preview

Pacific Medical Journal

Advanced search

Clinical course of the early postoperative period of phacoemulsification on the background of various schemes of antibacterial prophylaxis

https://doi.org/10.17238/PmJ1609-1175.2017.2.16-17

Abstract

Objective. The objective of the study is to analyze the effect of various types of antibacterial prophylaxis (local and systemic) on the severity of postoperative reactive inflammation in the early period after phacoemulsification. Methods. 185 patients - 246 eyes with age-related cataract - divided into two equal groups. Representatives of the 1st group (123 eyes) received instillations of levofloxacin within 3 days before the operation, representatives of the 2nd group (123 eyes) additionally - levofloxacin inside 500 mg once a day, starting the day before the intervention, for five days. The signs of reactive inflammation were evaluated according to the S.N. Fedorov and E.V. Yegorova classification at the 1, 3 and 10 days after the operation. Results. On the 1st and 3rd day after the surgery, significantly better results on the response from the moisture of the anterior chamber of the eye were noted among the patients of the 2nd group. On the 10th day, there were no significant differences between the groups. Conclusions. We can talk about a significant decrease in the severity of the reactive inflammatory process from the anterior chamber of the eye after phacoemulsification with systemic antibacterial prophylaxis with fluoroquinolones.

About the Authors

G. A. Fedyashev
Pacific State Medical University; Primorskiy Centre of Eye Microsurgery
Russian Federation


E. V. Eliseeva
Primorskiy Centre of Eye Microsurgery
Russian Federation


References

1. Белоусова Н.Ю. Экссудативно-воспалительная реакция глаза в хирургии катаракты: современный взгляд на проблему // Современные технологии в медицине. 2011. № 3. С. 134-141.

2. Гундорова Р.А., Капитонов Ю.А., Овечкин Н.И., Романова И.Ю. Современные тенденции в фармакотерапии инфекционных осложнений у пациентов с травматическими поражениями органа зрения // Рос. офтальмол. журн. 2012. № 4. С. 10-14.

3. Гурченок П.А. Антибактериалные препараты в профилактике осложнений факоэмульсификации катаракты: дис.. кан. мед. наук. СПб., 2009. 110 с.

4. Околов И.Н. Резистентность к антибиотикам нормальной микрофлоры конъюнктивы пациентов перед офтальмохирургическими операциями // Офтальмологические ведомости. 2008. Т. 1, № 4. С. 59-62.

5. Полянская Е.Г. Анатомо-топографические особенности переднего сегмента глаза после проведения факоэмульсификации катаракты с имплантацией интраокулярной линзы при псевдоэксфолиативном синдроме: автореф. дис.. канд. мед. наук. М., 2011. 26 с.

6. Федоров С.Н., Егорова Э.В. Ошибки и осложнения при имплантации искусственного хрусталика. М.: Микрохирургия глаза, 1992. 244 с.

7. Arikan S., Ozdek S., Aktas Z. [et al.]. Vitreous and aqueous penetration of intravitreally and orally administered moxifloxacin in an experimental rabbit model of fungal endophthalmitis // J. Pharm. Pharmacol. 2013. Vol. 65. Р. 659-664.

8. Cagini C., Fiore T., Piccinelli F. [et al.]. Penetration of Prulifloxacin in human aqueous humour following oral administration // Acta Ophthalmol. 2012. Vol. 90. Р. 661-662.

9. George J.M., Fiscella R., Blair M. [et al]. Aqueous and vitreous penetration of linezolid and levofloxacin after oral administration // J. Ocul. Pharmacol. Ther. 2010. Vol. 26, No. 6. P. 579-586.

10. Ishida M., Kataoka T., Niwa K. [et al.]. Efficient penetration into aqueous humor by administration of oral and topical levofloxacin // Ocul. Pharmacol. Ther. 2011. Vol. 27, No. 3. P. 247-250.

11. Sharma T., Kamath M.M., Kamath M.G. [et al.]. Aqueous penetration of orally and topically administered moxifloxacin // Br. J. Ophthalmol. 2015. Vol. 99. Р. 1182-1185.


Review

For citations:


Fedyashev G.A., Eliseeva E.V. Clinical course of the early postoperative period of phacoemulsification on the background of various schemes of antibacterial prophylaxis. Pacific Medical Journal. 2017;(2):16-17. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2017.2.16-17

Views: 301


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1609-1175 (Print)