Humoral factors of the immune answer at patients with hemorrhagic fever with nephritic syndrome in Primorsky Krai
Abstract
Results of studying of changes of the anti-hemo-agglutinating and neutralization antibodies at patients with the hemorrhagic fever with nephritic syndrome are submitted. By results of reaction of braking of hemagglutination on occasion at patients with moderate infection the more expressed immune answer is revealed, especial in an initial stage of illness, as against severe forms. The importance of use of reaction of braking of hemagglutination for the information on participation of the certain serotypes/genotypes of hantavirus in epidemic process is shown. Changes of specific antibodies at patients with various forms of disease in reaction of neutralization is investigated. The level of antibodies titer essentially did not depend on severity; the tendency to its higher value at patients with easy forms of disease however was traced in peak of illness and a phase of recovery.
About the Authors
I. G. Maksema
Scientific research institute of epidemiology and microbiology of the Siberian branch of the Russian Academy of Medical Science (Vladivostok)
Russian Federation
Russian Federation
G. G. Kompanets
Scientific research institute of epidemiology and microbiology of the Siberian branch of the Russian Academy of Medical Science (Vladivostok)
Russian Federation
Russian Federation
T. V. Kushnareva
Scientific research institute of epidemiology and microbiology of the Siberian branch of the Russian Academy of Medical Science (Vladivostok)
Russian Federation
Russian Federation
R. A. Slonova
Scientific research institute of epidemiology and microbiology of the Siberian branch of the Russian Academy of Medical Science (Vladivostok)
Russian Federation
Russian Federation
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Review
For citations:
Maksema I.G., Kompanets G.G., Kushnareva T.V., Slonova R.A. Humoral factors of the immune answer at patients with hemorrhagic fever with nephritic syndrome in Primorsky Krai. Pacific Medical Journal. 2008;(2):79-82. (In Russ.)
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