Monitoring of resistency to antibiotics of P. aeruginosa, agents of intrahospital infections
Abstract
Despite of the certain progress in antibacterial therapy of the heavy hospital infections caused by P. aeruginosa, the frequency of failures remains to the highest. Distinctions in intensity of formation and circulation of P. aeruginosa resistant to antibiotics are connected to distinctions in a policy of application of antibiotics in various hospitals. The received data testify to necessity of correction of reports empirical antibiotic therapy of intrahospital pneumonias in departments of intensive therapy. Results of molecule genetic typing have shown the low efficiency of disk‑diffusions method and prove the necessity of studying of sensitivity of microorganisms to antibiotics with method of serial delutions.
About the Authors
V. B. Turkutjukov
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
V. B. Shumatov
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
E. V. Slabenko
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
G. A. Smirnov
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
V. N. Krasnoshchekov
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
V. P. Borzov
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
L. M. Klimova
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
L. N. Lebedeva
Vladivostok State Medical University;
Primorye Antiplague Station;
City Clinical Hospital No. 2;
Primorye Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
Ussuriysk;
Vladivostok
References
1. Сидоренко С.В., Резван С.П., Стерхова Г.А., Грудинина С.А. // http://science.rambler.ru/db/author.html?id=1002658.
2. Страчунский Л.С., Решедько Г.К., Рябкова Е.Л. и др. Рекомендации по антимикробной терапии нозокомиальных инфекций, вызванных грамотрицательными бактериями, в отделениях реанимации и интенсивной терапии : пособие для врачей. – Смоленск: Боргес, 2002.
3. Finnan S., Morrissey J.P., O’Gara F., Fidelma Boyd E.G. // J. Clinical Microbiology. – 2004 – Vol. 42, No. 12. – P. 5783–5791.
4. Gamper M., Ganter B., Polito M.R., Haas D. // J. Mol. Biol. – 1992. Vol. 226. – P. 943–957.
5. Haley R.W., Culver D.H., White J.W. et al. // Am. J. Epidemiol. – 1985. – Vol. 121. – P. 159–167.
6. Iaconis J.P., Pitrin D.H., Sheikh W., Nadler H.L. // Clin. Infect. Dis. – 1977. – Vol. 24, Suppl. 2. – P. 191–196.
7. Pierard D., Emmerechts K., Lauwers S. // J. Antimicrob. Chemother. – 1998. – Vol. 41. – P. 443–450.
8. Siegman-Igra Y., Ravona R., Primerman H., Giladi M. // Intern. J. Infect Dis. – 1998. – Vol. 2. – P. 211–215.
Review
For citations:
Turkutjukov V.B., Shumatov V.B., Slabenko E.V., Smirnov G.A., Krasnoshchekov V.N., Borzov V.P., Klimova L.M., Lebedeva L.N. Monitoring of resistency to antibiotics of P. aeruginosa, agents of intrahospital infections. Pacific Medical Journal. 2007;(3):45-47. (In Russ.)
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