The influence of the stress-induced reduction of the testosterone level on the histochemical changes of genitals of rats
Abstract
In experiment on 18 male rats authors modeled sharp and chronic cold stress (–20°С on 20 min) in 4 groups of animals. Studied the changes of a testosterone level in plasma by radioimmune analysis and changes of activity of NADPHdiaphorase of the testicles and cavernous bodies by the histochemical method by Hope, Vincеnt (1989). The activity of enzyme was estimated cytophotometrically. The wide representation of the structures with active NADPHdiaphorase in the testicles and cavernous bodies is established. As a result of sharp cold stress the reduction in a testosterone level and increase of NADPHdiaphorase activity of the testicles and cavernous bodies on 4th, 7th and 14th day of the stress reaction was observed. The revealed changes can be the part of the pathogenesis of the sexual dysfunctions at stress‑reaction.
About the Authors
O. A. Dmitrieva
Vladivostok state medical university
Russian Federation
Russian Federation
B. V. Sherstyuk
Vladivostok state medical university
Russian Federation
Russian Federation
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Review
For citations:
Dmitrieva O.A., Sherstyuk B.V. The influence of the stress-induced reduction of the testosterone level on the histochemical changes of genitals of rats. Pacific Medical Journal. 2007;(3):55-57. (In Russ.)
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