ESTIMATION OF VALUE OF CIRCULATING IMMUNE COMPLEXES IN THE PATHOGENESIS OF THE HEMORRHAGIC FEVER WITH RENAL SYNDROME
Abstract
The results of studying of dynamics of circulating immune complexes at patients with hemorrhagic fever with renal syndrome are shown. The activity of process of formation of complexes depends on a clinical variant of illness only in early terms and reaches the maximal values by the 3rd week of disease. It is found, that in the feverish period of illness the circulating immune complexes of big size prevail. The dynamics of circulation of an antigen of a virus in blood is investigated as well as in structure of immune complexes. It is shown, that along with decrease in the maintenance of hantavirus antigen in blood by the period of early recovery there is an essential increase of frequency of detection of specific antigen in structure of circulating immune complexes.
About the Authors
I. G. Maksyoma
Scientific research institute of epidemiology and microbiology Siberian Branch of the Russian Academy of Medical Science;
Vladivostok State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
T. V. Kushnareva
Scientific research institute of epidemiology and microbiology Siberian Branch of the Russian Academy of Medical Science;
Vladivostok State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
R. A. Slonova
Scientific research institute of epidemiology and microbiology Siberian Branch of the Russian Academy of Medical Science;
Vladivostok State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
V. A. Ivanis
Scientific research institute of epidemiology and microbiology Siberian Branch of the Russian Academy of Medical Science;
Vladivostok State Medical University
Russian Federation
Vladivostok
Russian Federation
Vladivostok
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Review
For citations:
Maksyoma I.G., Kushnareva T.V., Slonova R.A., Ivanis V.A. ESTIMATION OF VALUE OF CIRCULATING IMMUNE COMPLEXES IN THE PATHOGENESIS OF THE HEMORRHAGIC FEVER WITH RENAL SYNDROME. Pacific Medical Journal. 2006;(4):35-38. (In Russ.)
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