STATE OF VASCULAR ENDOTHELIAL FUNCTION UNDER ACUTE CORONARY SYNDROME
Abstract
The authors have examined 75 patients aged 37-79 suffering from acute coronary syndrome, including 22 cases of instable angina pectoris, 29 cases of large-focal myocardial infarction, and 24 cases of microinfarction. Control group was comprised of 20 healthy persons of the same age and sex. The vasomotor function of endothelium was estimated by using noninvasive ultrasonic method depending on how brachial artery responded to reactive hyperemia and nitrate intake, while the nitric oxide-producing function of endothelium was determined by nitric oxide metabolite content in blood serum. The patients suffering from the acute coronary syndrome had the nitric oxide-producing endothelial function disturbed. At the same time the state of the vasomotor and nitric oxide-producing endothelial functions did not detect any abnormalities of the parameters under examination at patients with unfavorable outcomes of the acute coronary syndrome.
About the Authors
V. A. Nevzorova
Vladivostok State Medical University
Russian Federation
Russian Federation
E. S. Potapova
Vladivostok State Medical University
Russian Federation
Russian Federation
L. V. Rodionova
Vladivostok State Medical University
Russian Federation
Russian Federation
O. V. Nastradin
Vladivostok State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Nevzorova V.A., Potapova E.S., Rodionova L.V., Nastradin O.V. STATE OF VASCULAR ENDOTHELIAL FUNCTION UNDER ACUTE CORONARY SYNDROME. Pacific Medical Journal. 2004;(3):61-63. (In Russ.)
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