Radiation therapy and breast reconstruction
V. I. Apanasevich,
I. S. Gulian,
N. O. Nikiforova,
Y. Y. Petukhova,
O. V. Korshunova,
V. N. Kustov,
V. V. Temchenco https://doi.org/10.34215/1609-1175-2020-4-10-14
Abstract
Radiation therapy is an integral component of the treatment of breast cancer. Although its implementing after breast reconstruction sufficiently increases the number of complications, particularly capsular contractures. After having analyzed published materials and meta-analysis research the authors made a conclusion – if a patient is planned to have a breast reconstruction, it’s better to make it with her own tissue. On the other hand the risk of capsular contractures development significantly decreases when using acellular matrix and polyurethane shell to cover the implant. This fact gives hope that conflict between breast reconstruction and the necessity of the radiation therapy can be solved.
About the Authors
V. I. Apanasevich
Pacific State Medical University
Russian Federation
Russian Federation
MD, PhD, professor, Institute of Surgery,
2 Ostryakova Ave., Vladivostok, 690002
I. S. Gulian
Pacific State Medical University;
Far Eastern Federal University
Russian Federation
Russian Federation
MD, assistant, Institute of Surgery,
2 Ostryakova Ave., Vladivostok, 690002
N. O. Nikiforova
Pacific State Medical University
Russian Federation
Russian Federation
student,
2 Ostryakova Ave., Vladivostok, 690002
Y. Y. Petukhova
Primorsky Regional Cancer Center;
Pacific State Medical University
Russian Federation
Russian Federation
MD, deputy chief physician, 59 Russian St., Vladivostok, 690105;
postgraduate student
O. V. Korshunova
Pacific State Medical University
Russian Federation
Russian Federation
MD, PhD, research associate of the Central Research Institute,
2 Ostryakova Ave., Vladivostok, 690002
V. N. Kustov
Vladivostok Branch of the Customs Academy
Russian Federation
Russian Federation
leading researcher,
31 Fadeeva St., Vladivostok, 690034
V. V. Temchenco
Vladivostok Branch of the Customs Academy
Russian Federation
Russian Federation
leading researcher,
31 Fadeeva St., Vladivostok, 690034
References
1. Kaprin AD, Starinsky VV, Petrova GV, eds. The situation of oncological assistance to the population of Russia in 2017. Moscow; 2018 (In Russ).
2. Zikiryakhodzhaev AD, Shirokikh IM, Ablitsova NV, Ermoshchenkova MV, Kharchenko NV, Saribekyan EK, et al. Biological and synthetic materials in reconstructive surgery for breast cancer treatment (Literature review). Tumors of Female Reproductive System. 2018;14(1):28–37 (In Russ).
3. Zernov KY, Dashyan GA, Krivorotko PV, Novikov SN, Paltuev RM, Tabagua TT, et al. Breast reconstruction and radiotherapy. Malignant Tumors. 2017;22(1):30–6 (In Russ).
4. Hennequin C, Barillot I, Azria D, Belkacemi Y, Bollet M, Chauvet B, et al. Radiotherapy of breast cancer. Cancer Radiotherapy. 2016;20:139–46.
5. O’Halloran N, Lowery A, Kalinina O, Sweeney K, Malone C, McLoughlin R, et al. Trends in breast reconstruction practices in a specialized breast tertiary referral centre. BJS Open. 2017;1(5):148–57.
6. Yun JH, Diaz R, Orman AG. Breast reconstruction and radiation therapy. Cancer Control. 2018;25:1–7.
7. Robbins TH. Rectus abdominis myocutaneous flap for breast reconstruction. Aust N Z J Surg. 1979;49(5):527–30.
8. Crisera CA, Chang EI, Da Lio AL, Festekjian JH, Mehrara BJ. Immediate free flap reconstruction for advanced-stage breast cancer: Is it safe? Plast Reconstr Surg. 2011;128(1):32–41.
9. Schaverien MV, Macmillan RD, McCulley SJ. Is immediate autologous breast reconstruction with postoperative radiotherapy good practice? A systematic review of the literature. J Plast Reconstr Aesthet Surg. 2013;66(12):1637–51.
10. Chang EI, Liu TS, Festekjian JH, Da Lio AL, Crisera CA. Effects of radiation therapy for breast cancer based on type of free flap reconstruction. Plast Reconstr Surg. 2013;131(1):1e–8e.
11. Taghizadeh R, Moustaki M, Harris S, Roblin P, Farhadi J. Does post-mastectomy radiotherapy affect the outcome and prevalence of complications in immediate DIEP breast reconstruction? A prospective cohort study. J Plast Reconstr Aesthet Surg. 2015;68(10):1379–85.
12. Rochlin DH, Jeong AR, Goldberg L, Harris T, Mohan K, Seal S, et al. Postmastectomy radiation therapy and immediate autologous breast reconstruction: integrating perspectives from surgical oncology, radiation oncology, and plastic and reconstructive surgery. J Surg Oncol. 2015;111(3):251–7.
13. Garvey PB, Clemens MW, Hoy AE, Smith B, Zhang H, Kronowitz S, Butler C. Muscle-sparing TRAM flap does not protect breast reconstruction from postmastectomy radiation damage compared with the DIEP flap. Plast Reconstr Surg. 2014;133(2):223–33.
14. Stenina MB, Zhukova LG, Koroleva IA, Parakonnaya AA, Semiglazova TU, Tulandin SA, Frolova MA. Practical recommendations for the medicinal treatment of invasive breast cancer. RUSSCO. M.; 2017:105–21 (In Russ).
15. Carlson GW, Page AL, Peters K, Ashinoff R, Schaefer T, Losken A. Effects of radiation therapy on pedicled transverse rectus abdominis myocutaneous flap breast reconstruction. Ann Plast Surg. 2008;60(5):568–72.
16. Patel KM, Albino F, Fan KL, Liao E, Nahabedian MY. Microvascular autologous breast reconstruction in the context of radiation therapy: comparing two reconstructive algorithms. Plast Reconstr Surg. 2013;132(2):251–7.
17. Baumann DP, Crosby MA, Selber JC. Optimal timing of delayed free lower abdominal flap breast reconstruction after postmastectomy radiation therapy. Plast Reconstr Surg. 2011;127(3):1100–6.
18. Jagsi R, Momoh AO, Qi J. Impact of radiotherapy on complications and patient-reported outcomes after breast reconstruction. J Natl Cancer Inst. 2018;110(2):157–65.
19. Momoh AO, Ahmed R, Kelley BP. A systematic review of complications of implant-based breast reconstruction with prereconstruction and postreconstruction radiotherapy. Ann Surg Oncol. 2014;21(1):118–24.
20. Hughes K, Brown C, Perez V. The effect of radiotherapy on implant-based breast reconstruction in the setting of skin-sparing mastectomy: clinical series and review of complications. Anticancer Res. 2012;32(2):553–7.
21. Aristei C, Falcinelli L, Bini V. Expander/implant breast reconstruction before radiotherapy: outcomes in a single-institute cohort. Strahlenther Onkol. 2012;188(12):1074–9.
22. Chuba PJ, Stefani WA, Dul C, Szpunar S, Falk J, Wagner R, et al. Radiation and depression associated with complications of tissue expander reconstruction. Breast Cancer Res Treat. 2017; 164(3):641–7.
23. Cordeiro PG, Albornoz CR, McCormick B. What is the optimum timing of postmastectomy radiotherapy in two-stage prosthetic reconstruction: Radiation to the tissue expander or permanent implant? Plast Reconstr Surg. 2015;135(6):1509–17.
24. Collier P, Williams J, Edhayan G, Kanneganti K, Edhayan E. The effect of timing of postmastectomy radiation on implant-based breast reconstruction: a retrospective comparison of complication outcomes. Am J Surg. 2014;207(3):408–11.
25. Cordeiro PG, Albornoz CR, McCormick B, Hu Q, Van Zee K. The impact of postmastectomy radiotherapy on two-stage implant breast reconstruction: an analysis of long-term surgical outcomes, aesthetic results, and satisfaction over 13 years. Plast Reconstr Surg. 2014;134(4):588–95.
26. Yun Pu, Tong-Chun Mao, Yi-Ming Zhang. The role of postmastectomy radiation therapy in patients with immediate prosthetic breast reconstruction. A meta-analysis. Medicine (Baltimore). 2018;97(6):1–6.
27. Cagli B, Barone M, Ippolito E. Ten years experience with breast reconstruction after salvage mastectomy in previously irradiated patients: analysis of outcomes, satisfaction and well-being. Eur Rev Med Pharmacol Sci. 2016;20(22):4635–41.
28. Benediktsson K, Perbeck L. Capsular contracture around saline-filled and textured subcutaneously-placed implants in irradiated and non-irradiated breast cancer patients: five years of monitoring of a prospective trial. J Plast Reconstr Aesthet Surg. 2006;59(1):27–34.
29. Elswick SM, Harless CA, Bishop SN Prepectoral implant-based breast reconstruction with postmastectomy radiation therapy. Plast Reconstr Surg. 2018;142(1):1–12.
30. Sigalove S, Maxwell GP, Sigalove NM. Prepectoral implant-based breast reconstruction and postmastectomy radiotherapy: Shortterm outcomes. Plast Reconstr Surg Glob Open. 2017;5(12):e1631. doi: 10.1097/GOX.0000000000001631
31. Kim I, Park SO, Chang H. Ung Sik Jin. inhibition mechanism of acellular dermal matrix on capsule formation in expander–implant breast reconstruction after postmastectomy radiotherapy. Ann Surg Oncol. 2018;25:2279–87.
32. Salzberg CA, Ashikari AY, Berry C, Hunsicker LM. Acellular dermal matrix-assisted direct-to-implant breast reconstruction and capsular contracture: A 13-year experience. Plast Reconstr Surg. 2016;138(2):329–37.
33. Valdatta L, Cattaneo AG, Pellegatta I, Scamoni S, Minuti A, Cherubino M. Acellular dermal matrices and radiotherapy in breast reconstruction: A systematic review and metaanalysis of the literature. Plast Surg Int. 2014;472604. doi: 10.1155/2014/472604
34. Rancati A, Soderini A, Dorr J, Gercovich G, Tessari L, Gonzalez E. One-step breast reconstruction with polyurethane-covered implants after skin-sparing mastectomy. J Plast Reconstr Aesthet Surg. 2013;66(12):1671–5.
35. Pompei S, Arelli F, Labardi L, Marcasciano F, Evangelidou D, Ferrante G. Polyurethane implants in 2-stage breast reconstruction: 9-year clinical experience. Aesthet Surg J. 2017;37(2):171–6.
Review
For citations:
Apanasevich V.I., Gulian I.S., Nikiforova N.O., Petukhova Y.Y., Korshunova O.V., Kustov V.N., Temchenco V.V. Radiation therapy and breast reconstruction. Pacific Medical Journal. 2020;(4):10-14. (In Russ.) https://doi.org/10.34215/1609-1175-2020-4-10-14
Views:
612
Email this article 