Practical application of the cell block technique for the diagnostics of the tumors of the pancreas and of other localizations
https://doi.org/10.34215/1609-1175-2020-4-90-92
Abstract
Liquid-based material and traditional pap smears got during fine-needle biopsies of different tumors were analyzed. Cell-cycle blocks and monolayer pills were made from liquid-based material depending on the amount of cell structures. Original method using donor thrombocyte mass was implemented to create cell-cycle blocks, especially to condense and consolidate the sediment after centrifugation. After taking pancreas punctures different medical institutions in Vladivostok managed to form cell-cycle blocks in 71 cases from 2017 to 2019. In 9 cases (12.7%) the material was found to be diagnostically noninformative, in 15 cases (21.2%) – sufficient for morphological research, but inappropriate for immunohistochemistry. In 47 cases (66.1%) 206 immunohistochemical tests were made using 34 types of biomarkers.
About the Authors
E. A. Kotsyrbiy
Pacific State Medical University
Russian Federation
Russian Federation
MD, PhD, head of the Dept. of Pathology and Medical Jurisprudence,
2 Ostryakova Ave., Vladivostok, 690002
Y. N. Tychonov
Pacific State Medical University;
Primorkiy Regional Pathology Bureau
Russian Federation
Russian Federation
MD, senior lecturer of the Dept. of Pathology and Medical Jurisprudence, 2 Ostryakova Ave., Vladivostok, 690002;
pathologist, 4 Ostryakova Ave., Vladivostok, 690002
I. V. Nazarova
Primorkiy Regional Pathology Bureau
Russian Federation
Russian Federation
MD, PhD,
4 Ostryakova Ave., Vladivostok, 690002
I. O. Reznichek
Pacific State Medical University
Russian Federation
Russian Federation
student,
2 Ostryakova Ave., Vladivostok, 690002
A. N. Tumanina
Primorskiy Regional Oncological Dispensary
Russian Federation
Russian Federation
MD, head of the Endoscopic Department,
59 Russkaya St., Vladivostok, 690105
M. Z. Gorelik
Primorkiy Regional Pathology Bureau
Russian Federation
Russian Federation
MD, head,
4 Ostryakova Ave., Vladivostok, 690002
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Review
For citations:
Kotsyrbiy E.A., Tychonov Y.N., Nazarova I.V., Reznichek I.O., Tumanina A.N., Gorelik M.Z. Practical application of the cell block technique for the diagnostics of the tumors of the pancreas and of other localizations. Pacific Medical Journal. 2020;(4):90-92. (In Russ.) https://doi.org/10.34215/1609-1175-2020-4-90-92
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