Characteristics of the epidemiology and methods of detecting tuberculosis among children under 14 years old in high-burden area
https://doi.org/10.34215/1609-1175-2021-1-85-89
Abstract
Objective: To characterize epidemiology and methods of diagnosing tuberculosis among children under 14 in high-burden areas.
Methods: The data of the epidemic monitoring in Primorsky Regional Anti-Tuberculosis Hospital for the period from 2005 to 2019 was analyzed.
Results: The dependence of the epidemic indicators on the screening methods was proved. From 2005 to 2009 during both mass screening and additional examination of the children in a specialized medical organizations such medicine as tuberculin was used. On average tuberculosis was diagnosed among 37.2 % children during preventive examination. From 2010 to 2014 after introduction of the recombinant tuberculosis allergen (RTA) into anti-tuberculosis organizations practice this indicator had increased up to 56 %. Screening using RTA was introduced in 2014. After that tuberculosis medical detection among children has increased by 1.9 and 1.35 times in comparison with previous periods respectively.
Conclusions: RTA using improves tuberculosis infection screening among children population. It positively influences clinical structure of the first identified tuberculosis.
About the Authors
L. N. MotanovaRussian Federation
Lyudmila N. Motanova, MD, PhD, professor, Institute of Therapy and Instrumental Diagnostics.
2 Ostryakova Ave., Vladivostok, 690002
O. F. Konoval
Russian Federation
Olga F. Konoval, MD, head of the 4th Outpatient Department.
2 Pyatnadtsataya St., Vladivostok, 690041
References
1. Guidance for national tuberculosis programs on the management of tuberculosis in children. WHO; 2014.
2. Aksenova VA, Baryshnikova LA, Klevno NI, Kudlay DA. Screening of children and adolescents for tuberculosis infection in Russia - past, present, future. Tuberculosis and Lung Disease. 2019;97(9):59-67 (In Russ).
3. Aksenova VA, Levi DT, Alexandrova NV, Kudlay DA, Baryshnikova LA, Klevno NI. Tuberculosis in children: Modern methods of prevention and early diagnosis. Doctor. Ru. 2017;15:9-15 (In Russ).
4. Kudlai DA. Biomarkers and immunological tests. Experimental and clinical parallels of latent tuberculosis infection. Tuberculosis and Lung Diseases. 2020;98(8):63-74 (In Russ).
5. Slogotskaya L, Bogorodskaya E, Sentchichina O, Ivanova D, Nikitina G, Litvinov V, et al. Effectiveness of tuberculosis detection using a skin test with allergen recombinant (CFP-10-ESAT-6) in children. Eur Resp J. 2015;46(suppl 59):PA4524. doi: 10.1183/13993003.congress-2015.PA4524
6. Starshinova AA, Kudlai DA, Dovgalyuk IF, Basantsova NYu, Zinchenko YuS, Yablonsky PK. The effectiveness of the use of new methods of immunodiagnostics of tuberculosis infection in the Russian Federation. Pediatrics. 2019;98(4):229-35 (In Russ).
7. Kudlai DA, Starshinova AA, Dovgalyuk IF. Recombinant tuberculosis allergen: 10-year experience with the test in children and adolescents in the Russian Federation (meta-analysis data). Pediatrics. 2020;99(3):121-9 (In Russ).
8. Motanova LN, Lavrenyuk VV. Assessment of the tuberculosis situation in the Primorsky Territory over the past 14 years (2003-2016). Pacific Medical Journal. 2017;4:74-6 (In Russ).
9. Motanova LN, Kovalenko GE, Popova YuV. Experience of using Diaskintest in an area with an unfavorable epidemic situation. Tuberculosis and Lung Diseases. 2013;9:74-6 (In Russ).
Review
For citations:
Motanova L.N., Konoval O.F. Characteristics of the epidemiology and methods of detecting tuberculosis among children under 14 years old in high-burden area. Pacific Medical Journal. 2021;(1):85-89. (In Russ.) https://doi.org/10.34215/1609-1175-2021-1-85-89