Review of modern advances in X-ray photodynamic therapy
https://doi.org/10.34215/1609-1175-2025-1-5-9
Abstract
The development and application of photosensitizers excited by high-energy X-rays represent an addition to the standard method of photodynamic therapy. The use of such materials can overcome a serious disadvantage of photodynamic therapy, i.e., a treatment of superficially located tumors accessible to laser. This review presents current advances in the production methods, safety, and effectiveness of bioavailable compounds for X-ray-induced photodynamic therapy. The potential and prospects for the future application of such constructs in clinical practice are determined.
About the Authors
O. V. Shevchenko
Pacific State Medical University
Russian Federation
Russian Federation
Olga V. Shevchenko – researcher at the Multidisciplinary laboratory center,
2 Ostryakova Ave., Vladivostok, Primorsky Territory, 690002
V. B. Shumatov
Pacific State Medical University
Russian Federation
Russian Federation
2 Ostryakova Ave., Vladivostok, Primorsky Territory, 690002
E. V. Eliseeva
Pacific State Medical University
Russian Federation
Russian Federation
2 Ostryakova Ave., Vladivostok, Primorsky Territory, 690002
K. A. Yuryeva
Pacific State Medical University
Russian Federation
Russian Federation
2 Ostryakova Ave., Vladivostok, Primorsky Territory, 690002
M. A. Medkov
Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
Vladivostok
M. A. Belobeletskaya
Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
Vladivostok
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Review
For citations:
Shevchenko O.V., Shumatov V.B., Eliseeva E.V., Yuryeva K.A., Medkov M.A., Belobeletskaya M.A. Review of modern advances in X-ray photodynamic therapy. Pacific Medical Journal. 2025;(1):5-9. (In Russ.) https://doi.org/10.34215/1609-1175-2025-1-5-9
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