The terms of the burn wounds contamination with the nosocomial flora
https://doi.org/10.34215/1609-1175-2020-1-28-31
Abstract
Objective. The study objective it to analyze the dynamics of microbial content of burn wounds and to assess the markers of hospital-acquired infection (HAI) in different periods of hospitalization.
Methods: 617 microbiological samples from the surface of burn wounds of 515 patients in the period from the first to ninth days after the injury were analyzed. The presence of gramnegative bacteria Pseudomonas aeruginosa and Acinetobacter baumannii, multiresistant microorganisms and microbial associations was determined. Spectrophotometry was used to identify pathogens and plate method was used to assess microbial content of wounds.
Results: During treatment, there was change of pathogens associated with duration of stay in the hospital. With an increase in hospitalization, the degree of microbial contamination of wounds, the rate of gram-negative bacteria, multiresistant microorganisms, and microbial associations increased.
Conclusions: The greatest severity of all signs of nosocomial infection occurs on the 3–4th day of hospitalization in a burn care facility. This period can be considered ad a start of active contamination of burn wounds with nosocomial flora. To prevent this, it is necessary as early as possible, from 2–3 days after hospitalization to apply active strategy for treating burn wounds and closing burn surfaces.
About the Authors
K. V. Mitryashov
Far Eastern Federal University, School of biomedicine
Russian Federation
Russian Federation
MD, postgraduate student, Department of Clinical Medicine,
8 Sukhanova St., Vladivostok, 690950
S. V. Okhotina
Vladivostok State University of Economics and Service
Russian Federation
Russian Federation
PhD,
44 Partizansky Ave., Vladivostok, 690106
E. V. Shmagunova
Far Eastern Regional Medical Centre of FMBA
Russian Federation
Russian Federation
MD,
161 Sto Let Vladivostoku Ave., Vladivostok, 690022
A. U. Kiselev
Far Eastern Federal University, School of biomedicine
Russian Federation
Russian Federation
MD, PhD, associate professor, Department of Clinical Medicine,
8 Sukhanova St., Vladivostok, 690950
V. V. Usov
Far Eastern Federal University, School of biomedicine
Russian Federation
Russian Federation
MD, PhD, head of Department of Clinical Medicine,
8 Sukhanova St., Vladivostok, 690950
References
1. Alekseyev AA, Krutikov MG, Yakovlev VP. Burn infection: Etiology, pathogenesis, diagnosis, prevention and treatment. Moscow: Vuzovskaya Kniga; 2010. 416 p. (In Russ).
2. Mikhin IV. Burns and frostbite: A manual. Volgograd: VolgGMU Publishing House; 2012. 88 p. (In Russ).
3. Chukhraev AM, Kononenko KV, Lazarenko VA, Brechka VG. Vnutribolnichnye infectsii v chirurgictescom statsionare. Kursk: KGMU; 2004. 206 p. (In Russ).
4. Hlumcher FS, Dubrov SA, Kuchyn YL. Multi-resistant infections: Relevance, definition, mechanisms, prevailing pathogens, treatment, prevention. Science and Practice. 2014;1(2):129–49 (In Russ).
5. Church D, Elsayed S, Reid O, Winston B, Lindsay R. Burn wound infections. Clinical Microbiology Reviews. 2006;19(2):403–34.
6. Gordinskaya NA, Sabirova EV, Abramova NV, Dudareva EV, Nekaeva ES. The peculiarities of the causative agents of wound infection of patients with thermal trauma. Medical Almanac. 2012;5:181–3 (In Russ).
7. Fomicheva TD, Turkutyukov VB, Sotnichenko SA, Terekhov SM, Skurikhina YuE, Okrokov VG. Microbiological monitoring in the epidimiological surveillance system for purulent-sepyic infections in case of burn injury. Pasific Medical Journal. 2018;3:72–4 (In Russ).
8. Samartsev VA, Encheva YA, Kuznetsova MV, Karpunina TI. The peculiarities of burn wound contamination. Novosti Khirurgii. 2014;22(2):199–206 (In Russ).
9. AL-Aali KY. Microbial profile of burn wound infection in burn patients, Taif, Saudi Arabia. Archives of Clinical Microbiology. 2016;7(2). URL: http://www .acmicrob.com/archive/ipacmvolume-7-issue-2-year-2016.html (Accessed Nov. 10, 2018).
10. Mohapatra S, Gupta A, Agrawal K, Choudhry H, Deb M. Bacteriological profiles in burn patients within first twenty – four hours of injury. Int J Med Microbiol Tropic Dis. 2016;2(2):71–4.
11. Park H, Pham C, Paul E, Padiglione A, Lo C, Cleland H. Early pathogenic colonizers of acute burn wounds: A retrospective review. Burns. 2017;43(8):1757–65.
12. Posluszny J, Conrad P, Halerz M, Shankar R, Gamelii R. Surgical burn wound infections and their clinical implications. J Burn Care Res. 2011;32(2):324–33.
13. Maksyuta VA, Skvorcov YuR, Chmirev IV. The synthetic wound coverage after late escharectomy in deep burns. Bulletin of the Russian Military Medical Academy. 2012;1(37):140–4 (In Russ).
Review
For citations:
Mitryashov K.V., Okhotina S.V., Shmagunova E.V., Kiselev A.U., Usov V.V. The terms of the burn wounds contamination with the nosocomial flora. Pacific Medical Journal. 2020;(1):28-31. (In Russ.) https://doi.org/10.34215/1609-1175-2020-1-28-31
Views:
643
Email this article 