Preview

Pacific Medical Journal

Advanced search

Conjunctiva microflora composition and antibiotic sensitivity in patients of Primorsky territory, having cataract surgery

Abstract

Background. Study objective is an analysis of the composition and antibacterial drugs sensitivity of conjunctiva microflora in patients having cataract surgery. Methods. 185 patients (246 eyes) were examined, who had surgery in 2014-2015. Evaluation of composition of microflora conjunctival sac was performed prior to surgery. The sensitivity of microorganisms to antibiotics was determined by disk diffusion method. Results. In most cases 155 eyes (63.1 %) inoculation was positive. Most often distinguished Staphylococcus epidermidis (68 cases) and Staphylococcus aureus (44 cases). Only 36.9 % of patients (91 eyes) inoculation proved sterile. S. epidermidis showed resistance to oxacillin, lincomycin, clarithromycin and azithromycin, showing sensitivity to ampicillin and cephalosporins. Of the drugs used locally, it was increasingly resistant to tetracycline, chloramphenicol, gentamicin, and tobramycin. The sensitivity to antibiotics of S. aureus was significantly higher than the epidermal one. This microorganism showed 100 % sensitivity to oxacillin and lincomycin. Conclusions. The findings make it necessary the pre-operative antibiotic therapy for the prevention of infectious complications in the early postoperative ophthalmic surgery. The least resistance is allocated to own material microflora awarded to ciprofloxacin and levofloxacin, it is necessary to consider the appointment of antibiotics in perioperative accompanied by cataract.

About the Authors

G. A. Fedyashev
Pacific State Medical Univeristy; Primorsky Center of Eye Microsurgery
Russian Federation


E. V. Eliseeva
Pacific State Medical Univeristy
Russian Federation


References

1. Астахов С.Ю., Вохмяков А.В. Эндофтальмит: профилактика, диагностика, лечение // Офтальмологические ведомости. 2008. Т. 1, № 1. С. 35-45.

2. Бандурова Е.А., Шуматов В.Б., Елисеева Е.В. Локальный микробиологический мониторинг и антибиотикорезистентность основных патогенов у пациентов с хирургической патологией в отделении интенсивной терапией // Тихоокеанский медицинский журнал. 2012. № 2. С. 25-29.

3. Воронцова Т.Н., Бржеский В.В., М.В. Михайлова. Чувствительность и резистентность к антибактериальным препаратам микрофлоры конъюнктивальной полости у детей // Офтальмология. 2012. Т. 9, № 1. С. 83-91.

4. Вохмяков A.B., Околов И.Н., Гурченок П.А. Выбор оптимального антибиотика для профилактики инфекционных осложнений в офтальмохирургии // Клиническая офтальмология. 2007. Т. 8, № 1. С. 37-40.

5. Кочергин С.А., Чернакова Г.М., Клещева Е.А. [и др.] Иммунитет глазного яблока и конъюнктивальная микрофлора // Инфекция и иммунитет. 2012. Т. 2, № 3. С. 635-644.

6. Околов И.Н., Гурченок П.А. Резистентность к антибиотикам нормальной микрофлоры конъюнктивы пациентов передо офтальмохирургическими операциями // Офтальмологические ведомости. 2008. Т. 1, № 4. С. 59-62.

7. Endophthalmitis Study Group, European Society of Cataract & Refractive Surgeons. Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors // J. Cataract. Refract. Surg. 2007. Vol. 33. P 978-988.

8. Karthika N., Neelima. A., Ramchandran S. A study of normal bacterial flora of the conjunctiva in patients undergoing cataract surgery in a rural teaching hospital in R. R. district // J. Scientific and Innovative Research. 2014. Vol. 3, No. 2. P. 164-167.

9. Lalwani G.A., Flynn H.W Jr, Scott I.U. [et al.] Acute-onset endophthalmitis after clear corneal cataract surgery (1996-2005). Clinical features, causative organisms, and visual acuity outcomes // Ophthalmology. 2008. Vol. 115, No. 3. P 473-476.

10. Olson R., Donnenfeld E., Bucci F.A. [et al.] Methicillin resistance of Staphylococcus species among health care and nonhealth care workers undergoing cataract surgery // Clin. Ophthalmol. 2010. Vol. 4. P. 1505-1514.

11. Suto C., Morinaga M., Yagi T. [et al.] Conjunctival sac bacterial flora isolated prior to cataract surgery // Infect. Drug Resist. 2012. No. 5. Р. 37-41.


Review

For citations:


Fedyashev G.A., Eliseeva E.V. Conjunctiva microflora composition and antibiotic sensitivity in patients of Primorsky territory, having cataract surgery. Pacific Medical Journal. 2015;(4):56-58. (In Russ.)

Views: 303


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1609-1175 (Print)