Clinical and diagnostic aspects of dry eye syndrome and peripheral retina changes

Abstract

Objective. Research objective is to correlate the manifestation degree of dry eye syndrome (DES) and the severity of changes in peripheral retina parts during ophthalmological therapy. methods. The research includes 94 patients with DES of mild and medium severity. Patients got lacrimal substitute therapy and local anti-inflammatory therapy. We diagnosed the front eye surface: the assessment of personal amelioration according to OSDI questionnaire, detecting of tear breakup time, sample colored with fluorescein, Schirmer's test, ophthalmoscopic ex amination of the peripheral retina parts. Follow-up time is 6 months. Results. It was built the logit-regressive models, showing the possibility of degeneration occurrencein peripheral retina parts with the factors changes, characterizing the state of the front eye surface and lacrimal apparatus. Conclusions. The possibility of occurrence of significant and inconvertible changes in peripheral retina parts maintained while correlating with the lacrimal factors for a month after the treatment started. The therapy by the 3^rd months led to the break of connectivity of these factors.