Comparative informativity of the morphological, radiological and biomechanical criteria of osteointegration in experiment

Abstract

Background. The requirements of stomatologic practice and progress of medical materials technology determine the high intensity of experimental researches of new materials and technologies in the area of dental implantology. Methods. In the experiment of putting the screw titanic implants in femurs of rats in 4, 8 and 12 weeks the radiological, mechanical and morphological characteristics of the osteointegration zone have been studied. Results. On roentgenograms on 4th week of the experiment the circle osteointegration zone was visible. At morphological study the thin layer of the friable connecting tissue with the osteogenic centers was found. In12^th week osteointegration was finished: around the titanic implants the solid lamellar cover with sponge bone islets was found. Conclusions. General positive dynamics of osteointegration together with osteoconductive effect testified favouroubly the adequacy of the chosen experimental model. The small number of correlations between some indicators of the research methods was the basis for the recommendation of their use only in a complex: radiological research with radial densitometry of the osteointegration zone, mechanical study of the implant mobility and the classical morphological research added by the analysis of zone distribution of density of the organic matrix in the osteointegra-tion zone.