OSTEOARTHRITIS AND MICROCRYSTALLINE STRESS PHENOMENON
Abstract
The importance of the phenomenon of mineralization of cartilage due to osteoarthritis (OA) proved by an evidence of factors contributing to this process. The object of this study is to determine the clinical and pathogenetic significance of microcrystallisation of the articular cartilage caused by OA. Methods. The study embraced 110 persons operated on coxarthrosis from II to IV grades by (osteoarthritis grading system of) Kellgren and Lawrence and 50 persons undergone hip replacement after a coxal fracture. Methods of X-ray structure analysis used for examining tangential sections of a resected capitular of the femoral bone cartilage. Results. A phenomenon of mineralization of cartilage due to OA amounts 72.7 % of records, in C group - 16 %. The prevalence of microcrystallisation increased in accordance with the progression of radiographic symptoms of disease. Despite women have the greater predisposition to OA, mineralization of cartilage has an even frequency for both sexes. Conclusions. High prevalence of mineralization of articular cartilage due to OA compared with a comparable C group enables to consider the microcrystalline deposition to be an important attendant factor of the pathogenesis of this disease.
About the Authors
M. A. Kabalyk
Pacific State Medical University
Russian Federation
Russian Federation
A. I. Dubikov
Pacific State Medical University
Russian Federation
Russian Federation
T. Y. Petrikeeva
Pacific State Medical University
Russian Federation
Russian Federation
A. A. Karabtsov
Far East Geological Institute of the Russian Academy of Sciences Far East Branch
Russian Federation
Russian Federation
I. I. Kuzmin
Pacific State Medical University
Russian Federation
Russian Federation
A. V. Cherepovskiy
Pacific State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Kabalyk M.A., Dubikov A.I., Petrikeeva T.Y., Karabtsov A.A., Kuzmin I.I., Cherepovskiy A.V. OSTEOARTHRITIS AND MICROCRYSTALLINE STRESS PHENOMENON. Pacific Medical Journal. 2014;(1):70-74. (In Russ.)
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