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Neurons of spinal lamella X

https://doi.org/10.17238/PmJ1609-1175.2016.4.5-10

Abstract

The review presents extensive information about the position, form and functions of neurons of spinal lamella X in different animals that are the evidence of cells presence in autonomic nervous system (central nucleus), premotor interneurons and ectopic primary sensory neurons. With sufficient detail it is presented the results of the study of neuronal activity of acetylcholinesterase and nicotinamide adenine dinucleotide phosphate-diaphorase by histochemical methods, choline, gamma-aminobutyric acid, and nitric oxide synthase and calbindin by immunohistochemistry, supported by illustrations of their own research. These data allow the authors to believe that around the central canal of the spinal cord is functioning complex cluster of premotor neurons providing excitatory and inhibitory effect on motor neurons, preganglionic neurons of the autonomic nervous system, simpatotsity exercising innervation of the spinal cord vessels, as well as the primary sensory neurons.

About the Authors

V. V. Porseva
Yaroslavl State Medical University
Russian Federation


V. V. Shilkin
Yaroslavl State Medical University
Russian Federation


References

1. Матвеева Н.Ю., Калиниченко С.Г., Пущин И.И., Мотавкин П.А. Роль оксида азота в апоптозе нейронов сетчатки глаза плодов человека // Морфология. 2006. Т. 129, № 1. С. 42-48.

2. Мотавкин П.А., Черток В.М. Иннервация мозга // Тихоокеанский медицинский журнал. 2008. № 3. С. 11-23.

3. Пивченко П.Г. Структурная организация серого вещества спинного мозга человека и млекопитающих животных: автореф. дис.. д-ра мед. наук. Харьков, 1993. 38 с.

4. Порсева В.В. Возрастные преобразования ядер спинного мозга и спинномозговых ганглиев в норме и в условиях химической деафферентации: автореф. дис.. канд. мед. наук. Ярославль, 2006. 19 с.

5. Порсева В.В. Кальбиндин-иммунореактивные интернейроны промежуточной области и вентрального рога серого вещества спинного мозга белой крысы // Морфология. 2014. T 146, № 6. C. 21-26.

6. Порсева В.В., Шилкин В.В. NADPH-диафоразо-позитивные структуры спинного мозга и спинномозговых узлов // Морфология, 2010. Т. 137, № 2. С. 13-17.

7. Порсева В.В., Шилкин В.В., Стрелков А.А. [и др.]. Субпопуляции кальбиндин-иммунореактивных интернейронов дорсального рога спинного мозга мышей // Цитология. 2014. Т. 56, № 8. С. 612-618.

8. Черток В.М., Коцюба А.Е. Распределние NADPH-диафоразы и нейрональной NO-синтазы в ядрах продолговатого мозга // Морфология. 2013. Т. 144, № 6. С. 9-14.

9. Anelli R., Heckman C.J. The calcium binding proteins calbindin, parvalbumin, and calretinin have specific patterns of expression in the gray matter of cat spinal cord // J. Neurocytology. 2005. Vol. 34, No. 6. P. 369-385.

10. Antal M., Freund T.F., Polgar E. Calcium-binding proteins, parvalbuminand calbindin-D28k-immunoreactive neurons in the rat spinal cord and dorsal root ganglia: a light and electron microscopic study // J. Comp. Neurol. 1990. Vol. 295, No. 3. P. 467-484.

11. Banik, N.L., Matzelle, D.C., Gantt-Wilford G. [et al.]. Increased calpain content and progressive degradation of neurofilament protein in spinal cord injury // Brain Res. 1997. Vol. 752, No. 1-2. P. 301-306.

12. Barber R. P., Phelps P. E., Houser C. R. [et al.]. The morphology and distribution of neurons containing choline acetyltransferase in the adult rat spinal cord: an immunocytochemical study // J. Comp. Neurol. 1984. Vol. 229. P. 329-346.

13. Barber R.P., Vaughn J.E., Roberts E. The cytoarchitecture of GABAergic neurons in rat spinal cord // Brain Res. 1982. Vol. 238. P. 305-328.

14. Caillard O., Moreno H., Schwaller B. [et al.]. Role of the calcium-binding protein parvalbumin in short-term synaptic plasticity // Proc. Natl. Acad. Sci. USA. 2000. Vol. 97, No. 24. P. 1337213377.

15. Calka J., Zalecki M., Wasowicz K. [et al.]. A comparison of the distribution and morphology of ChAT-, VAChT-immunoreactive and AChE-positive neurons in the thoracolumbar and sacral spinal cord of the pig // Veterinarni Medicina. 2008. Vol. 53, No. 8. P. 434-444.

16. Deuchars S. A., Milligan C. J., Stornetta R. L. [et al.]. GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition // Neurosci. 2005. Vol. 25, No. 5. P. 1063-1070.

17. Fahandejsaadi A., Leung E., Rahaii R. [et al.]. Calbindin-D28K, parvalbumin and calretinin in primate lower motor neurons // Neuroreport. 2004. Vol. 15, No. 3. P. 443-448.

18. Freire M.A^., Tourinho S.C., Guimarâes J.S. [et al.]. Histo-chemical characterization, distribution and morphometric analysis of NADPH diaphorase neurons in the spinal cord of the agouti // Front. Neuroanat. 2008. Vol. 2. doi: 10.3389/ neuro.05.002.2008.

19. Gookin J.L., Rhoads J.M., Argenzio R.A. Inducible nitric oxide synthase mediates early epithelial repair of porcine ileum // Am. J. Physiol. Gastrointest. Liver Physiol. 2002. Vol. 283, No. 1. P. 157-168.

20. Gotts J., Edwards I., Deuchars S.A., Deuchars J. Co-localisation of the enzymes synthesising GABA and acetylcholine in the mouse spinal cord // Proc. Physiol. Soc. 31. 2014. PCA047.

21. Grant G., Koerber H.R. Spinal cord cytoarchitecture // The Rat Nervous System. 2004. Vol. 3. P. 121-128.

22. Jankowska E., Bannatyne B.A., Stecina K. [et al.]. Commissural interneurons with input from group I and II muscle afferents in feline lumbar segments: neurotransmitters, projections and target cells // J. Physiol. 2009. Vol. 587, No. 2. P. 401-418.

23. Kim J.J., Chang I.Y., Chung Y.Y. [et al.]. Immunohistochemi-cal studies on the calbindin D-28K and parvalbumin positive neurons in the brain stem and spinal cord after transection of spinal cord of rats // Korean J. Phys. Anthropol. 2002. Vol. 15, No. 4. P. 305-329.

24. Lee J.C., Hwang I.K., Cho J.H. [et al.]. Expression and changes of calbindin D-28k immunoreactivity in the ventral horn after transient spinal cord ischemia in rabbits // Neurosci Lett. 2004. Vol. 369, No. 2. P. 145-149.

25. Marsala J., Vanicky I., Marsala M. [et al.]. Reduced nicotinamide adenine dinucleotide phosphate diaphorase in the spinal cord of dogs // Neurosci. 1998. Vol. 85, No. 3. P. 847-862.

26. Megias M., Alvarez-Otero R., Pombal M.A. Calbindin and calretinin immunoreactivities identify different types of neurons in the adult lamprey spinal cord // J. Comp. Neurol. 2003. Vol. 455, No. 1. P. 72-85.

27. Morona R., Lopez J.M., Gonzalez A. Calbindin-D28k and calretinin immunoreactivity in the spinal cord of the lizard Gekko gecko: Colocalization with choline acetyltransferase and nitric oxide synthase // Brain Res. Bull. 2006. Vol. 69, No. 5. P. 519-534.

28. Motavkin P.A., Bakhtinov A.P. Postnatal development of human spinal cord ependymal innervation // Neuroscience and Behavioral Physiology. 1973. Vol. 6, No. 3. Р. 253-259.

29. Motavkin P.A., Dovbysh T.V. Cholinergic nervous apparatus of pia mater and brain blood vessels // Bull. Exp. Biol, Med. 1970. Vol. 70, No. 7. Р. 113-116.

30. Nagy J.I., Yamamoto T., Jordan L.M. Evidence for the cholinergic nature of C-terminals associated with subsurface cisterns in a-motoneurons of rat // Synapse. 1993. Vol. 15, No. 1. Р. 17-32.

31. Nahin R.L., Madsen A.M., Giesler G J. Anatomical and physiological studies of the gray matter surrounding the spinal cord central canal // Journal Comp. Neurol. 1983. Vol. 220. P. 321-335.

32. Polgar E., Sardella T.C., Tiong S.Y. [et al.]. Functional differences between neurochemically defined populations of inhibitory interneurons in the rat spinal dorsal horn // Pain. 2013. Vol. 154, No. 12. P. 2606-2615.

33. Porseva V.V. Topography and morphometric characteristics of NF200+ neurons in the gray matter of the spinal cord after capsaicin deafferentation // Neurosci. and Behav. Physiol. 2014. Vol. 44, No. 8. P. 919-923.

34. Schoenen J., Faull R.L.M. Spinal cord: cyto- and chemoarchitecture // The Human Nervous System. 2004. Vol. 2. P. 190-232.

35. Stepien A.E., Tripodi M., Arber S. Monosynaptic rabies virus reveals premotor network organization and synaptic specificity of cholinergic partition cells // Neuron. 2010. Vol. 68. P. 456-472.

36. Todd A.J. Neuronal circuitry for pain processing in the dorsal horn // Nature Reviews. 2010. Vol. 11. P. 823-836.

37. van Dijken H., Dijk J., Voorn P., Holstege J.C. Localization of dopamine D2 receptor in rat spinal cord identified with immunocytochemistry and in situ hybridization // Eur. J. of Neurosci. 1996. Vol. 8. P. 621-628.

38. Zagoraiou L., Akay T., Martin J.F. [et al.]. A cluster of cholinergic premotor interneurons modulates mouse locomotor activity // Neuron. 2009. Vol. 64. P. 645-662.


Review

For citations:


Porseva V.V., Shilkin V.V. Neurons of spinal lamella X. Pacific Medical Journal. 2016;61(4):5-10. (In Russ.) https://doi.org/10.17238/PmJ1609-1175.2016.4.5-10

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