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ROLE OF OSTEOPROTEGERIN IN THE DEVELOPMENT OF OSTEOPENIC SYNDROME IN CASE OF CHRONIC OBSTRUCTIVE LUNG DISEASE

Abstract

The medical observation of 55 patients aged 44-58 years old suffering from chronic obstructive lung disease has allowed to study the relationship between the levels of osteoprotegerin, markers of bone metabolism, tumour necrosis-a factor in blood serum and bone tissue mineral density. The Dual-energy X-ray absorptiometry was a technique used to measure the bone tissue mineral density. All this allowed diagnosing the osteopenic syndrome in 43 cases and confirming the direct correlation between the content of tumour necrosis-a factor and markers of bone resorption in blood serum, and between the content of osteoprotegerin and bone tissue mineral density.

About the Authors

E. A. Kochetkova
Vladivostok State Medical University
Russian Federation


K. A. Bourya
Vladivostok State Medical University
Russian Federation


L. G. Ugay
Vladivostok State Medical University
Russian Federation


E. A. Kotsyurbiy
Vladivostok State Medical University
Russian Federation


V. A. Nevzorova
Vladivostok State Medical University
Russian Federation


P. A. Lukiyanov
Pacific Institute of Bioorganic Chemistry of the FEB RAS
Russian Federation


S. A. Albavichus
Vladivostok State Medical University
Russian Federation


References

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Review

For citations:


Kochetkova E.A., Bourya K.A., Ugay L.G., Kotsyurbiy E.A., Nevzorova V.A., Lukiyanov P.A., Albavichus S.A. ROLE OF OSTEOPROTEGERIN IN THE DEVELOPMENT OF OSTEOPENIC SYNDROME IN CASE OF CHRONIC OBSTRUCTIVE LUNG DISEASE. Pacific Medical Journal. 2013;(1):20-22. (In Russ.)

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ISSN 1609-1175 (Print)