THE STATE OF ORAL CAVITY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES ACCORDING TO FUNCTIONAL AND LABORATORY SCREENING
Abstract
The medical examination of 80 patients with inflammatory bowel diseases allowed to detect the high occurrence of dental pathology like chronic catarrhal and chronic recurrent aphthous stomatitis, inflammatory diseases of paradontium, and find out hemodynamic disorders in paradontium and oral mucosa at different levels. The authors have pointed out the imbalance between pro-inflammatory and anti-inflammatory cytokines in oral fluid and high occurrence of Epstein-Bar viral infection that is indicative of the imbalance of local immunity factors. These changes may be responsible for high occurrence of dental pathology in patients with chronic cicatrizing enteritis and ulcerative colitis.
About the Authors
A. V. Tsimbalistov
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Russian Federation
N. S. Robakidze
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Russian Federation
S. Yu. Tyityuk
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Russian Federation
References
1. Адлер Г. Болезнь Крона и язвенный колит / пер. с нем. М.: ГЭОТАР-Мед., 2001. 527 с.
2. Антонова И.Н. Роль профессиональной гигиены полости рта в комплексном подходе к диагностике и лечению воспалительных заболеваний пародонта: автореф. дис.. канд. мед. наук. СПб., 2000. 17 с.
3. Барановский А.Ю., Симаненков В.И. Достижения и перспективы изучения функциональных и воспалительных заболеваний кишечника в СПбМАПО // Вестник МАПО. 2010. № 2. С. 121-134.
4. Грудянов А.И., Григорьян А.С., Фролова О.А. Диагностика в пародонтологии. М.: МИА, 2004. 49 с.
5. Кетлинский С.А., Симбирцев А.С. Цитокины. СПб.: Фолиант, 2008. 552 с.
6. Нейзберг Д.М., Левин М.Л. Характеристика местного иммунитета полости рта больных с заболеваниями желудочнокишечного тракта // Материалы VII конференции челюстнолицевых хирургов и стоматологов. СПб., 2001. С. 80-81.
7. Gibson J., Wray D., Bagg J. Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn>s disease // Oral Surg. Oral Med. Oral Pathol. 2000. Vol. 89, No. 2. P. 171-176.
8. Ishiguro Y. Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis // J. Gastroenterology. 1999. Vol. 34, No. l. P. 66-74.
9. Wright S., Sanders D.S., Lobo A.J. et al. Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease // Gut. 2004. Vol. 53, No. 8. P. 1123-1128.
Review
For citations:
Tsimbalistov A.V., Robakidze N.S., Tyityuk S.Yu. THE STATE OF ORAL CAVITY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES ACCORDING TO FUNCTIONAL AND LABORATORY SCREENING. Pacific Medical Journal. 2013;(1):51-53. (In Russ.)
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